Nokea
Which of the following is an adverse event of glucocorticoids:
- A. Arterial hypotension
- B. Hyponatremia
- C. Hypoglicemia
- D. Facilitate the development of infections
Correct Answer: D
Rationale: Glucocorticoids suppress immunity, increasing infection risk due to reduced inflammatory and immune responses.
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While caring for a patient with a history of hypothyroidism, the nurse expects which of the following medications to be included in the patient's medication list?
- A. Levothyroxine sodium (Synthroid)
- B. Estrogen (Estradiol)
- C. Iodine 131
- D. Carbimazole (Methimazole)
Correct Answer: A
Rationale: Levothyroxine (Synthroid) is the standard treatment for hypothyroidism, replacing thyroid hormone; carbimazole treats hyperthyroidism, and iodine 131 is for ablation.
A man is given a drug to reduce thyroid gland size and vascularity before surgical thyroidectomy. Which mechanism is responsible for its use in this setting?
- A. inhibition of the sodium/iodide symporter
- B. inhibition of thyroperoxidase
- C. inhibition of TSH secretion
- D. inhibition of thyroid hormone release
Correct Answer: D
Rationale: Inhibition of thyroid hormone release (e.g., by iodides) reduces gland size and vascularity pre-surgery.
The study of dose, distribution, metabolism & excretion of drugs in the body is known as
- A. Pharmacognosia
- B. Pharmacodynamics
- C. Dose effective study
- D. Pharmacotherapy
Correct Answer: B
Rationale: Pharmacodynamics studies drug effects, but pharmacokinetics (dose, distribution, metabolism, excretion) is more specific here; likely a typo in the document.
The standard dosage of St John's wort for the treatment of mild depression is:
- A. 300 mg daily
- B. 100 mg three times a day
- C. 300 mg three times a day
- D. 600 mg three times a day
Correct Answer: C
Rationale: 300 mg three times daily is the standard dose for St John's wort in mild depression.
A nurse is caring for a 77-year-old patient. The nurse would know that a normal physiologic change that must be considered when planning drug therapy, and is associated with aging is what?
- A. Blood volume decreases
- B. Subcutaneous tissue increases
- C. Total body water increases
- D. Muscle mass increases
Correct Answer: A
Rationale: Aging reduces blood volume, altering drug distribution and requiring dosage adjustments.