A 31-year-old woman with chronic anemia presents with a deepening of her voice and a decrease in breast size.
- A. Clomiphene
- B. Hydrochlorothiazide
- C. Furosemide
- D. Nandrolone
Correct Answer: D
Rationale: Nandrolone, an anabolic steroid, causes virilization (voice deepening, breast reduction).
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Long-acting beta-agonists (LTBAs) received a Black Box Warning from the U.S. Food and Drug Administration due to the:
- A. Risk of life-threatening dermatological reactions
- B. Increased incidence of cardiac events when LTBAs are used
- C. Increased risk of asthma-related deaths when LTBAs are used
- D. Risk for life-threatening alterations in electrolytes
Correct Answer: C
Rationale: The FDA Black Box Warning for LTBAs highlights increased asthma-related mortality risk, not dermatologic , cardiac , or electrolyte issues.
Tick the substance which changes the activity of an effector element but doesn't belong to second messengers:
- A. cAMP
- B. cGMP
- C. G-protein
- D. Calcium ions
Correct Answer: C
Rationale: G-protein is a transducer, not a second messenger, unlike cAMP, cGMP, and calcium.
Which of the following drugs is CORRECTLY paired with its ECG effects?
- A. Lidocaine; decreased QRS and PR intervals
- B. Metoprolol: increased QRS duration
- C. Flecainide: increased PR, QRS, and QT intervals
- D. Verapamil: increased PR interval
Correct Answer: D
Rationale: Verapamil slows AV conduction, increasing PR interval.
The nurse knows that which medication requires monitoring of thyroid function?
- A. Dofetilide
- B. Amiodarone
- C. Sotalol
- D. Flecainide
Correct Answer: B
Rationale: Amiodarone can cause hypo- or hyperthyroidism due to its iodine content, necessitating thyroid function monitoring.
A nurse is assessing a client who takes Lithium Carbonate for the treatment of Bipolar disorder. The nurse should recognize which of the following findings as a possible indication of toxicity to this medication?
- A. Severe hypertension
- B. Coarse tremors
- C. Constipation
- D. Muscle spasm
Correct Answer: B
Rationale: Coarse tremors are a common sign of lithium toxicity, indicating neurological effects.