Nokea
Mutations in receptor tyrosine kinases would most likely be associated with :
- A. Neurologic diseases
- B. Endocrine diseases
- C. Cancers
- D. Metabolic abnormalities
Correct Answer: C
Rationale: Receptor tyrosine kinases are often linked to uncontrolled cell growth when mutated, commonly associated with cancers.
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Infants and young children are at higher risk of ADRs due to:
- A. Immature renal function in school-age children
- B. Lack of safety and efficacy studies in the pediatric population
- C. Children's skin being thicker than adults, it is less likely to absorb dosages of topical medication
- D. Infant boys having a higher proportion of muscle mass, leading to a higher volume of distribution
Correct Answer: B
Rationale: Lack of pediatric studies increases ADR risk due to unestablished safety/efficacy, unlike renal maturity , skin thickness (C, false), or muscle mass (D, false).
A 31-year-old woman with chronic anemia presents with a deepening of her voice and a decrease in breast size.
- A. Clomiphene
- B. Hydrochlorothiazide
- C. Furosemide
- D. Nandrolone
Correct Answer: D
Rationale: Nandrolone, an anabolic steroid, causes virilization (voice deepening, breast reduction).
Which statement about clonidine is false
- A. Useful in the management of opiate withdrawal syndrome
- B. Claimed to have prophylactic value in migraine
- C. It is alpha-2 receptor stimulant
- D. It is safe on abrupt termination of treatment
Correct Answer: D
Rationale: Abrupt clonidine withdrawal can cause rebound hypertension.
A nurse is assessing a client who takes Lithium Carbonate for the treatment of Bipolar disorder. The nurse should recognize which of the following findings as a possible indication of toxicity to this medication?
- A. Severe hypertension
- B. Coarse tremors
- C. Constipation
- D. Muscle spasm
Correct Answer: B
Rationale: Coarse tremors are a common sign of lithium toxicity, indicating neurological effects.
A nurse is preparing to administer Haloperidol 2 mg PO every 12 hr. The amount available is haloperidol 1 mg/tablet. how many tablets should the nurse administer? (Round the answer to the nearest whole number. Do not use a trailing zero.)
- A. 2
- B. 6
- C. 1
- D. 8
Correct Answer: A
Rationale: Calculation: 2 mg ÷ 1 mg/tablet = 2 tablets, matching the provided answer.