Nokea
Which statement accurately describes a drug agonist?
- A. A drug that reacts with specific receptor sites on a cell and prevents the reaction of another chemical with a different receptor site on that cell
- B. A drug that interferes with the enzyme systems that act as catalysts for different chemical reactions
- C. A drug that interacts directly with receptor sites to cause the same activity that a natural chemical would cause at that site
- D. A drug that reacts with receptor sites to block normal stimulation, producing no effect
Correct Answer: C
Rationale: Agonists are drugs that produce effects similar to those produced by naturally occurring neurotransmitters, hormones, or other substances found in the body. Noncompetitive antagonists are drugs that react with certain receptor sites, preventing the reaction of another chemical with a different receptor site. Drug-enzyme interactions interfere with the enzyme systems that stimulate various chemical reactions.
You may also like to solve these questions
Drug which interferes with metabolism of theophylline is:
- A. Erythromycin
- B. Gentamicin
- C. Penicillin
- D. Furazolidone
Correct Answer: A
Rationale: Erythromycin inhibits P-450, increasing theophylline levels.
Isoproterenol produces maximal contraction of cardiac muscle in a manner similar to epinephrine. Which of the following best describe isoproterenol?
- A. Fuller agonist
- B. Partial agonist
- C. Irreversible antagonist
- D. Inverse agonist
Correct Answer: A
Rationale: Isoproterenol's maximal effect similar to epinephrine indicates it is a full agonist at beta receptors.
A patient is prescribed a buccal medication. The nurse would instruct the patient to place the drug at which location?
- A. Under the tongue
- B. Against the cheek mucous membrane
- C. Inside the rectum
- D. At the back of the tongue
Correct Answer: B
Rationale: Buccal drugs are placed in the mouth against the mucous membranes of the cheek in either the upper or lower jaw. Sublingual medications are placed under the tongue. Rectal suppositories are inserted into the rectum. Oral medications are placed at the back of the tongue.
Thyroxin is contributed in all listed processes except one:
- A. Increase tissue demand of oxygen consumption
- B. Activating protein, carbohydrates and fats metabolism
- C. Increase the main metabolism
- D. Decrease the main metabolism
Correct Answer: D
Rationale: Thyroxine (T4) increases metabolism, not decreases it, by enhancing oxygen use and nutrient breakdown.
The patient is prescribed a medication that was just placed in Phase IV study. The patient tells the nurse, This medication is too expensive. Could the doctor order a generic form of this medication? What is the nurse's most accurate response?
- A. Medications are not produced in generic form until the patent expires, which normally takes several years.
- B. You can request the generic form but the binder used may make the drug less effective for this medication.
- C. The generic form of the medication would not be any less expensive because this is a relatively new medication.
- D. Generic medications are lower quality drugs and that would mean you would not be getting the best treatment available.
Correct Answer: A
Rationale: When a new drug enters the market, it is given a time-limited patent; generic forms of the medication cannot be produced until the patent expires. Because no generic version of this drug will exist because it is so new, it is impossible to predict what binder will be used or what the cost would be.