Nokea
Which of the following drugs is associated with the reaction of tendon dysfunction?
- A. Digitalis
- B. Niacin
- C. Tetracycline
- D. Fluoroquinolones
Correct Answer: D
Rationale: The correct answer is D: Fluoroquinolones. Fluoroquinolones are known to be associated with tendon dysfunction due to their potential to cause tendinitis and tendon rupture. This adverse effect is thought to be related to the drug's ability to disrupt collagen synthesis and structure in tendons. Digitalis (A) is used to treat heart conditions, niacin (B) for cholesterol, and tetracycline (C) for bacterial infections, none of which are linked to tendon dysfunction.
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Which of the following conditions are not treated with Barbiturates?
- A. Seizures
- B. Hypotension
- C. Insomnia
- D. Anxiety
Correct Answer: B
Rationale: Barbiturates are central nervous system depressants used to treat seizures, insomnia, and anxiety. However, they can worsen hypotension as they can cause vasodilation and decrease blood pressure. Choice B is correct because using barbiturates in hypotensive patients can lead to further lowering of blood pressure, potentially causing harm. Choices A, C, and D are incorrect as barbiturates are commonly used to treat seizures, insomnia, and anxiety, respectively, due to their sedative and anticonvulsant properties.
Which of the following is not a known effect of the drug Clozapine?
- A. Agranulocytosis
- B. Antipsychotic
- C. Used for Schizophrenia
- D. Hyperactivity
Correct Answer: D
Rationale: The correct answer is D: Hyperactivity. Clozapine is an antipsychotic drug used for schizophrenia treatment. Agranulocytosis is a known severe side effect of Clozapine. Hyperactivity is not a known effect of Clozapine, as it actually has a sedative effect due to its mechanism of action in the brain. Therefore, option D is the correct answer. Options A, B, and C are incorrect as agranulocytosis is a known side effect, Clozapine is an antipsychotic drug, and it is commonly used for schizophrenia treatment.
A drug ending in the suffix (tidine) is considered a ______.
- A. Antidepressant
- B. Protease inhibitor
- C. Beta antagonist
- D. H antagonist
Correct Answer: D
Rationale: The correct answer is D: H antagonist. Drugs ending in the suffix (tidine) typically belong to the class of histamine H2-receptor antagonists. These drugs work by blocking the action of histamine on H2 receptors in the stomach, reducing the production of stomach acid. This is commonly used to treat conditions such as peptic ulcers and gastroesophageal reflux disease.
Explanation of other choices:
A: Antidepressant - Drugs ending in (pramine) or (ine) are more commonly associated with antidepressants.
B: Protease inhibitor - Drugs ending in (navir) are typically protease inhibitors used in antiviral therapy.
C: Beta antagonist - Drugs ending in (olol) are beta-blockers, which are used to treat conditions such as hypertension and heart disease, not related to (tidine) suffix.
Which of the following is the antidote for Heparin toxicity?
- A. Protamine
- B. Methylene blue
- C. N-acetylcysteine
- D. Glucagon
Correct Answer: A
Rationale: Protamine is the antidote for Heparin toxicity because it binds to Heparin and forms a stable complex, neutralizing its anticoagulant effects. Protamine sulfate is positively charged, while Heparin is negatively charged, allowing them to bind effectively. Methylene blue is used to treat methemoglobinemia, not Heparin toxicity. N-acetylcysteine is used for acetaminophen overdose, and Glucagon is used for beta-blocker overdose.
Which of the following conditions is not treated with Nifedipine?
- A. Angina
- B. Arrhythmias
- C. Hypertension
- D. Fluid retention
Correct Answer: D
Rationale: Nifedipine is a calcium channel blocker primarily used to treat angina, arrhythmias, and hypertension due to its vasodilatory effect. However, it does not treat fluid retention as it does not have diuretic properties. Therefore, the correct answer is D. Choice A, B, and C are incorrect because nifedipine is commonly used to manage these conditions.