Nokea
Which of the following is not a side effect of the ACE Inhibitor (Captopril)?
- A. Rash
- B. Angioedema
- C. Cough
- D. Congestion
Correct Answer: D
Rationale: The correct answer is D: Congestion. ACE Inhibitors like Captopril do not typically cause congestion as a side effect. The main reason is that ACE inhibitors work by dilating blood vessels, which helps reduce blood pressure and improve blood flow. Congestion is more commonly associated with conditions like allergies or upper respiratory infections.
A: Rash - Possible side effect of ACE inhibitors, but not specific to Captopril.
B: Angioedema - Rare but serious side effect of ACE inhibitors, including Captopril.
C: Cough - Common side effect of ACE inhibitors due to increased bradykinin levels.
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Which of the following conditions is not treated with epinephrine?
- A. Renal disease
- B. Asthma
- C. Hypotension
- D. Glaucoma
Correct Answer: A
Rationale: The correct answer is A: Renal disease. Epinephrine is not used to treat renal disease because it can potentially worsen kidney function. Epinephrine is used in asthma to dilate the airways, in hypotension to increase blood pressure, and in glaucoma to reduce intraocular pressure. Treating renal disease with epinephrine can lead to further complications due to its effect on blood flow and kidney function. Therefore, renal disease is not treated with epinephrine to avoid exacerbating kidney issues.
Which of the following conditions is not typically treated with Hydrochlorothiazide?
- A. CHF
- B. HTN
- C. Nephritis
- D. Hypercalciuria
Correct Answer: C
Rationale: Hydrochlorothiazide is a diuretic commonly used to treat hypertension (HTN) and congestive heart failure (CHF) by reducing blood volume and lowering blood pressure. Nephritis is an inflammatory condition of the kidneys, not typically treated with Hydrochlorothiazide as it may worsen kidney function. Hypercalciuria, excessive calcium in the urine, can be managed with Hydrochlorothiazide as it helps reduce calcium excretion. Therefore, the correct answer is C (Nephritis), as it is not typically treated with Hydrochlorothiazide due to its potential impact on kidney function.
Which of the following is classified as a class IA Sodium Channel blocker?
- A. Quinidine
- B. Disopyramide
- C. Aminodarone
- D. Propafenone
Correct Answer: A
Rationale: The correct answer is A: Quinidine. Quinidine is a class IA antiarrhythmic drug that blocks sodium channels in a use-dependent manner, which means it preferentially blocks channels that are open or have a rapid firing rate during depolarization. This action results in a decrease in conduction velocity and refractory period. Disopyramide is a class IA antiarrhythmic but does not specifically block sodium channels. Amiodarone is a class III antiarrhythmic that primarily affects potassium channels. Propafenone is a class IC antiarrhythmic that has minimal effects on sodium channel blockade. Therefore, Quinidine is the correct choice as a class IA sodium channel blocker.
A drug ending in the suffix (navir) is considered a ______.
- A. Antidepressant
- B. Protease inhibitor
- C. Beta antagonist
- D. H antagonist
Correct Answer: B
Rationale: The correct answer is B: Protease inhibitor. Drugs ending in the suffix (navir) are commonly used to inhibit protease enzymes in viruses, particularly in the treatment of HIV/AIDS. Protease inhibitors disrupt viral replication by preventing the cleavage of viral proteins, thus inhibiting the production of new infectious viral particles.
Choice A, Antidepressant, is incorrect as drugs used to treat depression usually end in (ine) or (pram).
Choice C, Beta antagonist, is incorrect as drugs affecting beta receptors typically end in (olol) or (lol).
Choice D, H antagonist, is incorrect as drugs targeting histamine receptors usually end in (ine) or (idine).
Which of the following is considered a class IA Sodium Channel blocker?
- A. Mexiletine
- B. Amiodarone
- C. Quinidine
- D. Procainamide
Correct Answer: D
Rationale: The correct answer is D: Procainamide. Procainamide is a class IA antiarrhythmic drug that blocks sodium channels, prolonging the action potential duration. This helps to stabilize the heart's rhythm. Mexiletine (A) is a class IB antiarrhythmic drug that blocks sodium channels with fast recovery kinetics. Amiodarone (B) is a class III antiarrhythmic drug that prolongs repolarization by blocking potassium channels. Quinidine (C) is a class IA antiarrhythmic drug that also blocks sodium channels, but it is not a class IB sodium channel blocker like Procainamide.