Nokea
Which of the following conditions is not treated with Methotrexate?
- A. Sarcomas
- B. Leukemias
- C. Ectopic pregnancy
- D. Rheumatic fever
Correct Answer: D
Rationale: The correct answer is D: Rheumatic fever. Methotrexate is not typically used to treat rheumatic fever as it is an autoimmune inflammatory condition, not typically responsive to Methotrexate. Methotrexate is commonly used to treat sarcomas, leukemias, and ectopic pregnancies due to its ability to inhibit cell proliferation. Sarcomas and leukemias are types of cancers, while ectopic pregnancy is a condition where a fertilized egg implants outside the uterus.
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A drug ending in the suffix (tidine) is considered a ______.
- A. Antidepressant
- B. Protease inhibitor
- C. Beta antagonist
- D. H antagonist
Correct Answer: D
Rationale: The correct answer is D: H antagonist. Drugs ending in the suffix (tidine) typically belong to the class of histamine H2-receptor antagonists. These drugs work by blocking the action of histamine on H2 receptors in the stomach, reducing the production of stomach acid. This is commonly used to treat conditions such as peptic ulcers and gastroesophageal reflux disease.
Explanation of other choices:
A: Antidepressant - Drugs ending in (pramine) or (ine) are more commonly associated with antidepressants.
B: Protease inhibitor - Drugs ending in (navir) are typically protease inhibitors used in antiviral therapy.
C: Beta antagonist - Drugs ending in (olol) are beta-blockers, which are used to treat conditions such as hypertension and heart disease, not related to (tidine) suffix.
Which of the following conditions is not treated with epinephrine?
- A. Renal disease
- B. Asthma
- C. Hypotension
- D. Glaucoma
Correct Answer: A
Rationale: The correct answer is A: Renal disease. Epinephrine is not used to treat renal disease because it can potentially worsen kidney function. Epinephrine is used in asthma to dilate the airways, in hypotension to increase blood pressure, and in glaucoma to reduce intraocular pressure. Treating renal disease with epinephrine can lead to further complications due to its effect on blood flow and kidney function. Therefore, renal disease is not treated with epinephrine to avoid exacerbating kidney issues.
In which of the following cases is Lansoprazole not used?
- A. Gastritis
- B. Peptic Ulcers
- C. Zollinger-Ellison syndrome
- D. Thalamus hypertrophy
Correct Answer: D
Rationale: Rationale: Lansoprazole is a proton pump inhibitor used to treat conditions related to excess stomach acid. Thalamus hypertrophy is not a condition affecting stomach acid production, making it unrelated to Lansoprazole use. A: Gastritis, B: Peptic Ulcers, and C: Zollinger-Ellison syndrome all involve excessive stomach acid secretion, hence Lansoprazole is used in these cases. Thalamus hypertrophy does not involve stomach acid issues, making it the correct answer.
Potassium-sparing diuretics primarily affect which part of the kidney?
- A. Proximal convoluted tubule
- B. Loop of Henle
- C. Collecting duct
- D. Distal convoluted tubule
Correct Answer: D
Rationale: The correct answer is D: Distal convoluted tubule. Potassium-sparing diuretics, such as spironolactone, act on the distal convoluted tubule by blocking the aldosterone receptor, which leads to decreased sodium reabsorption and potassium retention. This mechanism helps to promote diuresis while preventing potassium loss. Choices A, B, and C are incorrect because potassium-sparing diuretics do not primarily affect the proximal convoluted tubule, loop of Henle, or collecting duct in the kidney.
Which of the following is the antidote for lead poisoning?
- A. Naloxone
- B. Nitrite
- C. CaEDTA
- D. Dialysis
Correct Answer: C
Rationale: The correct answer is C: CaEDTA. Calcium disodium ethylenediaminetetraacetic acid (CaEDTA) is a chelating agent used to treat lead poisoning by binding to lead ions in the bloodstream and enhancing their excretion through urine. It forms stable complexes with lead, reducing its toxicity. Naloxone (A) is an opioid receptor antagonist, used to reverse opioid overdose. Nitrite (B) is used in cyanide poisoning. Dialysis (D) is not effective in removing lead from the body as lead is not effectively dialyzable.