A drug ending in the suffix (navir) is considered a ______.
- A. Antidepressant
- B. Protease inhibitor
- C. Beta antagonist
- D. H antagonist
Correct Answer: B
Rationale: The correct answer is B: Protease inhibitor. Drugs ending in the suffix (navir) are commonly used to inhibit protease enzymes in viruses, particularly in the treatment of HIV/AIDS. Protease inhibitors disrupt viral replication by preventing the cleavage of viral proteins, thus inhibiting the production of new infectious viral particles.
Choice A, Antidepressant, is incorrect as drugs used to treat depression usually end in (ine) or (pram).
Choice C, Beta antagonist, is incorrect as drugs affecting beta receptors typically end in (olol) or (lol).
Choice D, H antagonist, is incorrect as drugs targeting histamine receptors usually end in (ine) or (idine).
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A healthcare provider is assessing a client who is taking levothyroxine. The healthcare provider should recognize that which of the following findings is a manifestation of levothyroxine overdose?
- A. Insomnia
- B. Constipation
- C. Drowsiness
- D. Hypoactive deep-tendon reflexes
Correct Answer: A
Rationale: The correct answer is A: Insomnia. Levothyroxine is a thyroid hormone replacement medication used to treat hypothyroidism. An overdose of levothyroxine can lead to hyperthyroidism symptoms, such as insomnia. This occurs due to an excess of thyroid hormone in the body, which can increase metabolism and disrupt sleep patterns. The other choices (B: Constipation, C: Drowsiness, D: Hypoactive deep-tendon reflexes) are not typical manifestations of a levothyroxine overdose. Constipation and drowsiness are more commonly associated with hypothyroidism, the condition being treated with levothyroxine. Hypoactive deep-tendon reflexes are not a typical symptom of either hypothyroidism or hyperthyroidism.
Which of the following is classified as a class IA Sodium Channel blocker?
- A. Quinidine
- B. Disopyramide
- C. Aminodarone
- D. Propafenone
Correct Answer: A
Rationale: The correct answer is A: Quinidine. Quinidine is a class IA antiarrhythmic drug that blocks sodium channels in a use-dependent manner, which means it preferentially blocks channels that are open or have a rapid firing rate during depolarization. This action results in a decrease in conduction velocity and refractory period. Disopyramide is a class IA antiarrhythmic but does not specifically block sodium channels. Amiodarone is a class III antiarrhythmic that primarily affects potassium channels. Propafenone is a class IC antiarrhythmic that has minimal effects on sodium channel blockade. Therefore, Quinidine is the correct choice as a class IA sodium channel blocker.
Which of the following conditions is not treated with Nifedipine?
- A. Angina
- B. Arrhythmias
- C. Hypertension
- D. Fluid retention
Correct Answer: D
Rationale: Nifedipine is a calcium channel blocker primarily used to treat angina, arrhythmias, and hypertension due to its vasodilatory effect. However, it does not treat fluid retention as it does not have diuretic properties. Therefore, the correct answer is D. Choice A, B, and C are incorrect because nifedipine is commonly used to manage these conditions.
Which of the following is not a side effect of Sympathoplegics (Clonidine)?
- A. Hypertension
- B. Difficulty breathing
- C. Dry oral cavity
- D. Lethargic behavior
Correct Answer: A
Rationale: The correct answer is A: Hypertension is not a side effect of Sympathoplegics (Clonidine). Sympathoplegics are medications that inhibit the sympathetic nervous system, leading to decreased heart rate and blood pressure. Therefore, hypertension is not a common side effect. Choices B, C, and D are incorrect because difficulty breathing, dry oral cavity, and lethargic behavior are potential side effects of Sympathoplegics due to their central nervous system depressant effects.
Which of the following is not a side effect of the cholinoreceptor blocker (Atropine)?
- A. Increased pulse
- B. Diarrhea
- C. Constipation
- D. Mydriasis
Correct Answer: B
Rationale: The correct answer is B: Diarrhea. Atropine, a cholinoreceptor blocker, inhibits acetylcholine, causing decreased GI motility leading to constipation. Atropine also increases pulse rate due to reduced vagal tone (A). It causes mydriasis by blocking cholinergic receptors in the eye (D). Diarrhea is not a typical side effect of atropine due to its anticholinergic properties.