An organ that can be classified as both an endocrine and exocrine gland is the
- A. hypothalamus.
- B. thymus gland.
- C. pancreas.
- D. pituitary gland.
Correct Answer: C
Rationale: The correct answer is C: pancreas. The pancreas is classified as both an endocrine gland, producing hormones like insulin and glucagon, and an exocrine gland, secreting digestive enzymes into the small intestine. This dual functionality makes it unique among the other options. The hypothalamus (A) is primarily an endocrine gland involved in hormone regulation, while the thymus gland (B) is solely an endocrine gland responsible for T-cell maturation. The pituitary gland (D) is also an endocrine gland that regulates various bodily functions but does not have exocrine functions like the pancreas.
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The normal response to increased serum osmolality is the release of
- A. aldosterone from the adrenal cortex, which stimulates sodium excretion by the kidney.
- B. ADH from the posterior pituitary gland, which stimulates the kidney to reabsorb water.
- C. mineralocorticoids from the adrenal gland, which stimulate the kidney to excrete potassium.
- D. calcitonin from the thyroid gland, which increases bone resorption and decreases serum calcium levels.
Correct Answer: B
Rationale: ADH (antidiuretic hormone) is released to promote water reabsorption by the kidneys when serum osmolality increases.
Match the correct hormone pair that have antagonistic effects?
- A. Calcitonin-parathyroid hormone
- B. Glucagon-gastrin
- C. Estrogen-testosterone
- D. Gonadotropic releasing hormone-luteinizing hormone
Correct Answer: a
Rationale: The correct answer is A: Calcitonin-parathyroid hormone.
1. Calcitonin lowers blood calcium levels by inhibiting bone breakdown, while parathyroid hormone raises blood calcium levels by stimulating bone breakdown.
2. This hormone pair directly opposes each other in regulating blood calcium levels.
3. Choices B, C, and D do not involve hormones with antagonistic effects on the same physiological process.
Dobutamine is used in the treatment of:
- A. Hypertension
- B. Heart failure
- C. Glaucoma
- D. Arrhythmia
Correct Answer: B
Rationale: Dobutamine is a positive inotrope that increases cardiac contractility, making it a suitable choice for treating heart failure by improving cardiac output. It is not typically used for hypertension, glaucoma, or arrhythmias. Hypertension is usually managed with antihypertensive medications like ACE inhibitors or beta-blockers. Glaucoma is treated with medications that reduce intraocular pressure. Arrhythmias are commonly managed with antiarrhythmic drugs or procedures such as ablation. Therefore, choice B, heart failure, is the correct answer for the use of dobutamine.
Iodination of thyroid hormones is mediated by __________.
- A. lysosomes in the cell
- B. the Golgi apparatus
- C. colloid endocytosis
- D. peroxidase enzymes
Correct Answer: D
Rationale: The correct answer is D: peroxidase enzymes. Peroxidase enzymes are responsible for catalyzing the iodination process of thyroid hormones in the thyroid gland. They facilitate the incorporation of iodine atoms into tyrosine residues within thyroglobulin to form thyroid hormones T3 and T4. Lysosomes (choice A) are involved in cellular waste disposal, not iodination. The Golgi apparatus (choice B) is responsible for processing and packaging proteins, not iodination. Colloid endocytosis (choice C) is the process of internalizing colloid-containing vesicles in thyroid follicular cells, but it is not directly involved in iodination.
Mrs. Good, a diabetic, states that she has taken the oral hypoglycemic, phenformin hydrochloride (DBI), for years. From this information, the nurse knows that Mrs. Good
- A. has not been receiving close medical supervision
- B. has moderately severe diabetes
- C. has active beta-cell function
- D. will soon need to switch to insulin therapy
Correct Answer: A
Rationale: Phenformin has been largely discontinued due to safety concerns, and it suggests the patient may not be receiving proper diabetes management.