Nokea
A 21-year-old patient says no one in his family has type 1 diabetes mellitus but he has had it since childhood. He asks how his diabetes was transmitted to him. The nurse should explain to him that this disease is
- A. a single gene disorder
- B. a chromosome disorder
- C. an acquired genetic disorder
- D. a multifactorial genetic disorder
Correct Answer: D
Rationale: Type 1 diabetes is considered a multifactorial genetic disorder influenced by multiple genes and environmental factors rather than being caused by a single gene or chromosome.
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Which of the following statements is false about dendritic cells
- A. Found in tissues
- B. Are sessile cells only found in lymph nodes
- C. Express high levels of MHC molecules
- D. Best at activating naïve T cells
Correct Answer: B
Rationale: The correct answer is B because dendritic cells are not only found in lymph nodes but also in tissues. These cells are antigen-presenting cells that capture and present antigens to T cells. A, C, and D are true statements about dendritic cells: A) They are found in tissues, C) They express high levels of MHC molecules for antigen presentation, and D) They are best at activating naive T cells due to their ability to prime adaptive immune responses.
A patient with wheezing and coughing caused by an allergic reaction to penicillin is admitted to the emergency department (ED). Which of these medications do you anticipate administering first?
- A. methylprednisolone (Solu-Medrol) 100 mg IV
- B. cromolyn sodium (Intal) 20 mg per nebulizer
- C. albuterol (Proventil) 0.5 mL per nebulizer
- D. aminophylline 500 mg IV over 20 minutes
Correct Answer: C
Rationale: Albuterol is a bronchodilator that acts quickly to relieve wheezing and coughing caused by bronchospasm. It is the first-line treatment for acute allergic reactions affecting the airways. The other medications may be used as adjuncts but are not as immediately effective in relieving bronchospasm.
What are haematopoietic stem cells responsible for?
- A. Differentiating into lymph nodes
- B. Producing immune cells
- C. Generating cytokines
- D. Suppressing pathogens directly
Correct Answer: B
Rationale: Haematopoietic stem cells are responsible for producing immune cells. These stem cells differentiate into various types of blood cells, including white blood cells that play a crucial role in the immune system. They do not differentiate into lymph nodes (A), generate cytokines (C), or suppress pathogens directly (D). The correct answer (B) aligns with the primary function of haematopoietic stem cells in the production of immune cells.
What are the three main principles of adaptive immunity?
- A. Respond, Replace, Repair
- B. Recognize, Respond, Remember
- C. Resist, Retain, Recruit
- D. React, Replicate, Restore
Correct Answer: B
Rationale: The three main principles of adaptive immunity are Recognize, Respond, Remember.
1. Recognize: Immune system identifies specific pathogens through antigen recognition.
2. Respond: Immune response is triggered to eliminate the pathogen.
3. Remember: Immune system forms memory cells for faster and stronger response upon re-exposure.
Other options are incorrect:
A: Respond, Replace, Repair - Incorrect as it does not reflect the key processes of adaptive immunity.
C: Resist, Retain, Recruit - Incorrect as these terms do not accurately describe the adaptive immune response.
D: React, Replicate, Restore - Incorrect as it does not encompass the essential principles of adaptive immunity.
A patient is admitted with acute myelogenous leukemia and a history of Hodgkin’s lymphoma. What is the nurse likely to find in the patient’s history?
- A. Work as a radiation chemist
- B. Epstein-Barr virus diagnosed in vitro
- C. Intense tanning throughout the lifetime
- D. Alkylating agents for treating the Hodgkin’s lymphoma
Correct Answer: D
Rationale: Alkylating agents used to treat Hodgkin’s lymphoma can increase the risk of developing secondary malignancies like acute myelogenous leukemia.