Nokea
A 28 year old male patient present with a painless sore in his penis and blood * test confirms Treponema pallidum. Which of the following agent is the treatment of choice that can be given as a single dose?
- A. Benzathine penicillin
- B. Ceftriaxone
- C. Vancomycin
- D. Aztreonam
Correct Answer: A
Rationale: The correct answer is A: Benzathine penicillin. The treatment of choice for syphilis caused by Treponema pallidum is penicillin. Benzathine penicillin is preferred due to its long-acting nature, providing sustained therapeutic levels. It is given as a single dose for early-stage syphilis. Ceftriaxone, vancomycin, and aztreonam are not effective against Treponema pallidum and are not recommended for the treatment of syphilis. Benzathine penicillin remains the first-line treatment due to its efficacy and established effectiveness against syphilis.
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Mrs. T. also complains of hoarseness, which results from
- A. increased capillary permeability
- B. a secondary respiratory infection
- C. a large thyroid tumor pressing on the larynx
- D. a psychologic illness
Correct Answer: C
Rationale: The correct answer is C because hoarseness can be caused by a large thyroid tumor pressing on the larynx, affecting vocal cord function. This physical obstruction directly interferes with the ability of the vocal cords to vibrate properly, leading to hoarseness. Increased capillary permeability (A) would not result in hoarseness. A secondary respiratory infection (B) may cause coughing or throat irritation, but not hoarseness specifically. A psychologic illness (D) would not directly cause hoarseness as it is a physical symptom related to the vocal cords.
A 75 year old man is suffering from benign prostatic hypertrophy and is being * treated with terazosin. Which of the following adverse reaction would be expected taking this drug?
- A. Erectile dysfunction
- B. Orthostatic hypotension
- C. GI distress
- D. Gynecomastia
Correct Answer: B
Rationale: The correct answer is B: Orthostatic hypotension. Terazosin is an alpha-1 blocker commonly used to treat BPH. It can cause vasodilation, leading to a drop in blood pressure, especially when standing up suddenly, resulting in orthostatic hypotension. This is because terazosin relaxes smooth muscle in blood vessels, causing dilation and blood pooling in the extremities. Erectile dysfunction (A) is not a common side effect of terazosin. GI distress (C) is less likely because terazosin does not directly affect the gastrointestinal system. Gynecomastia (D) is not a typical side effect of terazosin since it does not impact hormone levels significantly.
A patient has had three pregnancies and two live births. The nurse would record this information as gravida _____, para _____, AB _____
- A. 2; 2; 1
- B. 3; 2; 0
- C. 3; 2; 1
- D. 3; 3; 1
Correct Answer: C
Rationale: The correct answer is C: 3; 2; 1. Gravida refers to the total number of pregnancies, including the current one. As the patient has had three pregnancies, the gravida is 3. Para indicates the number of live births, so since the patient has had two live births, the para is 2. AB represents the number of abortions or miscarriages, which is 1 in this case. Therefore, the correct way to record this patient's obstetric history is gravida 3, para 2, AB 1.
Choice A (2; 2; 1) is incorrect because the patient has had three pregnancies, not two. Choice B (3; 2; 0) is incorrect as it does not account for the abortion/miscarriage that occurred. Choice D (3; 3; 1) is also incorrect because the patient has had two live births, not three.
A patient with HIV-AIDS being treated with combined antiviral drugs and immunosuppressive agents, develops an opportunistic infection caused by Pneumocystis carinii. Which of the following drugs most likely be used in the treatment of pulmonary infection caused by P. carinii?
- A. Metronidazole
- B. Carbenicillin
- C. Trimethoprim/Sulfamethoxazole
- D. Penicillin G
Correct Answer: C
Rationale: The correct answer is C: Trimethoprim/Sulfamethoxazole. This combination is the first-line treatment for Pneumocystis carinii pneumonia in patients with HIV-AIDS due to its efficacy against the organism. Trimethoprim inhibits dihydrofolate reductase, while sulfamethoxazole inhibits dihydropteroate synthase, both essential enzymes for folate synthesis in bacteria and protozoa like P. carinii. Metronidazole (A) is used for anaerobic infections, Carbenicillin (B) is a penicillinase-resistant penicillin used for Gram-negative infections, and Penicillin G (D) is a narrow-spectrum antibiotic mainly used for Gram-positive infections.
Desmopressin reduces urine volume in which of the following condition? *
- A. Central (neurogeni
- B. diabetes insipidus
- C. Renal (nephrogeni
- D. diabetes insipidus
Correct Answer: B
Rationale: Desmopressin reduces urine volume in diabetes insipidus by mimicking the action of vasopressin, which is deficient in this condition. It helps to increase water reabsorption in the kidneys, leading to decreased urine output. Central and nephrogenic diabetes insipidus are not directly treated with desmopressin as they involve different underlying mechanisms. Therefore, choice B is the correct answer.