Nokea
A 6 year old child was admitted to the emergency unit with suspicion of an accidental overdose of chlordiazepoxide. Which of the following antagonists may be administered as part of the initial treatment?
- A. Flumazenil
- B. Naloxone
- C. Fomepizole
- D. Nalorphine
Correct Answer: A
Rationale: Flumazenil reverses benzodiazepine (e.g., chlordiazepoxide) overdose.
You may also like to solve these questions
Jack, age 8, has attention deficit disorder (ADD) and is prescribed methylphenidate (Ritalin). He and his parents should be educated about the side effects of methylphenidate, which are:
- A. Slurred speech and insomnia
- B. Bradycardia and confusion
- C. Dizziness and orthostatic hypotension
- D. Insomnia and decreased appetite
Correct Answer: D
Rationale: Insomnia and appetite suppression are common methylphenidate side effects.
An agonist is substance that:
- A. Interacts with the receptor without producing any effect
- B. Interacts with the receptor and initiates changes in cell function, producing various effects
- C. Increases concentration of another substance to produce effect
- D. Interacts with plasma proteins and doesn't produce any effect
Correct Answer: B
Rationale: An agonist binds receptors and activates them, producing a biological effect.
The U.S. Drug Enforcement Administration:
- A. Registers manufacturers and prescribers of controlled substances
- B. Regulates NP prescribing at the state level
- C. Sanctions providers who prescribe drugs off-label
- D. Provides prescribers with a number they can use for insurance billing
Correct Answer: A
Rationale: The DEA registers those handling controlled substances , not state NP rules , off-label sanctions , or insurance numbers .
The action of 'gliptins' is different from other antidiabetic agents because they:
- A. Have a low risk for hypoglycemia
- B. Are not associated with weight gain
- C. Close ATP-dependent potassium channels in the beta cell
- D. Act on the incretin system to indirectly increase insulin production
Correct Answer: D
Rationale: Gliptins enhance incretin activity, boosting insulin secretion without hypoglycemia risk , unlike sulfonylureas .
Protein binding of a drug helps in
- A. Distribution
- B. Prolonging half life
- C. Limiting metabolism
- D. All of the above
Correct Answer: D
Rationale: Protein binding affects distribution (bound drugs stay in plasma), prolongs half-life (less free drug available for clearance), and limits metabolism (bound drug is less accessible to enzymes).