Nokea
A 64-year-old woman with a history of type 2 diabetes is diagnosed with heart failure. Which of the following medications would be a poor choice for controlling her diabetes?
- A. Exenatide
- B. Glyburide
- C. Nateglinide
- D. Rosiglitazone
Correct Answer: D
Rationale: Rosiglitazone can worsen heart failure due to fluid retention and edema.
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What describes the action of a drug on the body?
- A. Pharmacodynamics
- B. Pharmacokinetics
- C. Microbiology
- D. Physiology
Correct Answer: A
Rationale: Pharmacodynamics studies the effects of a drug on the body, including mechanisms of action and therapeutic effects, unlike pharmacokinetics, which focuses on drug movement.
A nurse is monitoring a client who takes aspirin 81 mg PO daily. The nurse should identify which of the following manifestations as adverse effects of daily aspirin therapy? (Select one that does not apply.)
- A. Hypertension
- B. Coffee-ground emesis
- C. Tinnitus
- D. Nausea
Correct Answer: A
Rationale: Aspirin can cause GI bleeding , tinnitus , and nausea ; 'possessias' is likely a typo.
Sitagliptin has been approved for:
- A. Monotherapy in once-daily doses
- B. Combination therapy with metformin
- C. Both 1 and 2
- D. Neither 1 nor 2
Correct Answer: C
Rationale: Sitagliptin is approved for monotherapy and with metformin , offering flexible type 2 diabetes management.
Drugs that are designated Schedule II by the U.S. Drug Enforcement Administration:
- A. Are known teratogens during pregnancy
- B. May not be refilled; a new prescription must be written
- C. Have a low abuse potential
- D. May be dispensed without a prescription unless regulated by the state
Correct Answer: B
Rationale: Schedule II drugs (e.g., opioids) require new prescriptions without refills due to high abuse potential, unlike teratogenicity or OTC status .
The routine monitoring recommended for low molecular weight heparin is:
- A. INR every 2 days until stable, then weekly
- B. aPTT every week while on therapy
- C. Factor Xa levels if the patient is pregnant
- D. White blood cell count every 2 weeks
Correct Answer: C
Rationale: Factor Xa levels may be monitored in pregnancy with LMWH; routine INR or aPTT isn't needed due to predictable pharmacokinetics.