A nurse is caring for a client who has a new prescription for Phenelzine for the treatment of depression. Which of the following indicates that the client has developed an adverse effect of this medication?
- A. Orthostatic hypotension
- B. Hearing loss
- C. Gastrointestinal bleeding
- D. Weight loss
Correct Answer: A
Rationale: Phenelzine, an MAOI, commonly causes orthostatic hypotension due to its effect on blood pressure regulation.
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You are the home health nurse caring for a 77-year-old patient with congestive heart failure. When assessing this patient, in relation to their drug therapy, what is one thing that would be important for you to include in your assessment?
- A. Patient's age
- B. Required lifestyle changes
- C. Family members in the community
- D. Compliance with nutritional recommendations
Correct Answer: B
Rationale: Lifestyle changes (e.g., salt restriction) impact CHF drug therapy efficacy and adherence, critical for assessment.
All of following are examples of prodrugs except
- A. Levodopa
- B. Enlapril
- C. Omeprazole
- D. Indomethacin
Correct Answer: D
Rationale: Prodrugs (e.g., levodopa, enalapril, omeprazole) are inactive until metabolized. Indomethacin is active as administered.
This graph illustrates the dose-response relationship for the effect of the beta agonist isoproterenol on an isolated perfused heart, both alone and in the presence of different fixed concentrations of Drug X. Based upon the data shown, Drug X is most likely a(n):
- A. beta agonist
- B. competitive antagonist
- C. irreversible antagonist
- D. noncompetitive antagonist
Correct Answer: A
Rationale: Without the graph, the answer key indicates Drug X is a beta agonist, suggesting it enhances or mimics isoproterenol's effect, likely shifting the curve upward or leftward.
Azathioprine has significant adverse drug effects, including:
- A. Hypertension
- B. Hirsutism
- C. Risk of cancer
- D. Gingival hyperplasia
Correct Answer: C
Rationale: Azathioprine increases cancer risk (e.g., lymphoma) via immunosuppression; other effects (A, B, D) are less prominent.
A nurse reviewing a client's health record notes a new prescription for Lisinopril 10 mg PO once every day. The nurse should identify this as which of the following types of prescription?
- A. Single
- B. Stat
- C. Routine
- D. Standing
Correct Answer: C
Rationale: A daily dose (once every day) indicates a routine prescription for ongoing treatment.