A naïve lymphocyte:
- A. Does not yet express antigen receptors
- B. Is not yet considered mature
- C. Has not yet been activated by antigen
- D. Is found only in primary lymphoid tissues
Correct Answer: C
Rationale: Step-by-step rationale:
1. Naïve lymphocytes have antigen receptors but have not been activated by antigen.
2. Activation is necessary for their differentiation into effector cells.
3. Naïve lymphocytes are considered mature as they have completed development.
4. They circulate in secondary lymphoid tissues, not just primary lymphoid tissues.
Summary:
Choice C is correct because naïve lymphocytes have antigen receptors but have not been activated by antigen. Choices A, B, and D are incorrect because naïve lymphocytes do express antigen receptors, are considered mature, and can be found in both primary and secondary lymphoid tissues.
You may also like to solve these questions
Identify the following types of cells that do HIV preferentially infect.
- A. Memory cells
- B. Helper T cells
- C. Cytotoxic T cells
- D. Natural killer cells
Correct Answer: B
Rationale: The correct answer is B: Helper T cells. HIV preferentially infects Helper T cells because they express the CD4 receptor, which serves as the primary binding site for the virus. Once infected, HIV impairs the Helper T cells' function, leading to immune system dysfunction. Memory cells (A), Cytotoxic T cells (C), and Natural killer cells (D) are not the primary targets of HIV infection as they do not express the CD4 receptor necessary for HIV entry and replication. Helper T cells are crucial for orchestrating immune responses, making them the primary target for HIV infection.
Which pathway of the complement system involves properdin, Factor B, and Factor D?
- A. Classical pathway
- B. Alternative pathway
- C. Lectin pathway
- D. Terminal pathway
Correct Answer: B
Rationale: The correct answer is B: Alternative pathway. This pathway involves properdin, Factor B, and Factor D. Properdin stabilizes the C3 convertase complex formed by Factor B and Factor D, leading to the amplification of the complement cascade. The other choices are incorrect because:
A: Classical pathway is initiated by antigen-antibody complexes binding to C1q.
C: Lectin pathway is activated by lectins binding to carbohydrates on pathogen surfaces.
D: Terminal pathway involves the formation of the membrane attack complex.
Vibrations from the sound waves are amplified by
- A. the eardrum
- B. Anvi
- C. Stirrup
- D. All above
Correct Answer: D
Rationale: The correct answer is D: All above. The vibrations from sound waves are amplified by the eardrum, Anvil (also known as the Incus), and Stirrup (also known as the Stapes), which are the three tiny bones in the middle ear. The sound waves travel through the ear canal and hit the eardrum, causing it to vibrate. The vibration is then transmitted through the Anvil to the Stirrup, which amplifies the vibrations and sends them to the inner ear. Each of these three components plays a crucial role in the process of amplifying sound vibrations for better auditory perception. Therefore, all three choices are correct in this context.
Which of the following is considered a defining characteristic of a TH2 response?
- A. Production of IgM antibodies
- B. Activation of CTL
- C. Recruitment and activation of neutrophils
- D. Production of IgE antibodies
Correct Answer: D
Rationale: The correct answer is D: Production of IgE antibodies. A TH2 response is characterized by the production of IgE antibodies, which are essential in allergic reactions. IgM antibodies (A) are produced during the primary immune response. Activation of CTL (B) is associated with a TH1 response. Neutrophils (C) are primarily involved in the innate immune response and are not specific to TH2 responses. In summary, the production of IgE antibodies is a defining characteristic of a TH2 response, distinguishing it from other immune responses.
An allogenic hematopoietic stem cell transplant is considered as treatment for a patient with acute myelogenous leukemia. What information should the nurse include when teaching the patient about this procedure?
- A. There is no risk for graft-versus-host disease because the donated marrow is treated to remove cancer cells
- B. The patient’s bone marrow will be removed,treated stored and then reinfused after intensive chemotherapy
- C. Peripheral stem cells are obtained from a donor who has a human leukocyte antigen (HLA) match with the patient
- D. There is no need for posttransplant protective isolation because the stem cells are infused directly into the blood
Correct Answer: C
Rationale: Peripheral stem cells from an HLA-matched donor are used in allogenic transplants.