A nurse is administering an IV infusion of amphotericin B. The nurse would be alert for which of the following adverse reactions during the first 30 to 60 minutes of the infusion?
- A. Muscle pain
- B. Hypotension
- C. Nausea
- D. Decreased renal function
- E. Chills
Correct Answer: B,C,E
Rationale: When the nurse administers amphotericin B by IV infusion, immediate adverse reactions can occur within 15 to 20 minutes of beginning the infusion, including nausea, vomiting, hypotension, tachypnea, fever, and chills; therefore, it is important for the nurse to carefully monitor the client's temperature, pulse, respirations, and blood pressure during the first 30 to 60 minutes of treatment.
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A nurse would expect to administer antihelminthic therapy cautiously to which of the following clients?
- A. Clients who are lactating
- B. Clients with hepatic impairment
- C. Clients with anemia
- D. Clients with diabetes
- E. Clients with renal impairment
Correct Answer: A,B,C,E
Rationale: Antihelminthic drugs should be used cautiously in lactating clients and clients with hepatic or renal impairment and malnutrition or anemia.
A client is receiving amphotericin B IV. The nurse identifies a nursing diagnosis of Impaired Comfort related to medication administration. The nurse determines that the plan of care was effective when which outcome is achieved?
- A. Client remains free from rigors.
- B. Client exhibits a blood pressure within acceptable parameters.
- C. Client maintains a patent IV infusion site.
- D. Client maintains a urine output of at least 30 mL/hour.
- E. Client demonstrates procedure for cleaning involved area.
Correct Answer: A,B,C
Rationale: The patient receiving amphotericin B IV can experience rigors, hypotension, and problems with the IV infusion site. Therefore, remaining free from rigors and maintaining a stable blood pressure and a patent IV infusion site would indicate that the plan of care for impaired comfort is successful. A urine output of 30 mL/hour would be an indicator of adequate renal tissue perfusion. Cleaning the involved area would not be appropriate because the client has a systemic fungal infection.
The primary health care provider has prescribed quinine for a client. The patient is also taking warfarin. Which of the following would be most important for the nurse to keep in mind about this combination when providing care to the patient?
- A. Quinine absorption is increased.
- B. Metabolism of quinine is increased.
- C. The patient is at increased risk for bleeding.
- D. The patient's risk for a heart attack is increased.
Correct Answer: C
Rationale: Combining warfarin with quinine increases the risk of bleeding. There is no risk of increased absorption or increased metabolism and no increased risk of heart attack associated with taking warfarin and quinine.
A group of nursing students are reviewing information about fungal infections. The students demonstrate understanding of the information when they identify which of the following as a superficial fungal infection?
- A. Aspergillosis
- B. Cryptococcal meningitis
- C. Thrush
- D. Malaria
Correct Answer: C
Rationale: Thrush is also oral candidiasis, a superficial fungal infection of the oral mucosa. Aspergillosis and cryptococcal meningitis are systemic fungal infections. Malaria is a protozoal infection.
A group of nursing students are reviewing information about helminthes. The students demonstrate understanding when they identify which of the following as a helminth?
- A. Roundworms
- B. Pinworms
- C. Ringworms
- D. Hookworms
- E. Tapeworms
Correct Answer: A,B,D,E
Rationale: Roundworms, pinworms, hookworms, and tapeworms are examples of helminths. Ringworm is a fungal infection.
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