Roach's Introductory Clinical Pharmacology 11th Edition - Antifungal and Antiparasitic Drugs Related

Review Roach's Introductory Clinical Pharmacology 11th Edition - Antifungal and Antiparasitic Drugs related questions and content

A nurse is administering an IV infusion of amphotericin B. The nurse would be alert for which of the following adverse reactions during the first 30 to 60 minutes of the infusion?

  • A. Muscle pain
  • B. Hypotension
  • C. Nausea
  • D. Decreased renal function
  • E. Chills
Correct Answer: B,C,E

Rationale: When the nurse administers amphotericin B by IV infusion, immediate adverse reactions can occur within 15 to 20 minutes of beginning the infusion, including nausea, vomiting, hypotension, tachypnea, fever, and chills; therefore, it is important for the nurse to carefully monitor the client's temperature, pulse, respirations, and blood pressure during the first 30 to 60 minutes of treatment.