A nurse is caring for a client who is prescribed omeprazole for a duodenal ulcer. The client is also taking benzodiazepines for the management of a seizure disorder. The nurse would assess the client for which of the following?
- A. Decreased absorption of the proton pump inhibitor
- B. Risk for toxic level of benzodiazepines
- C. Increased risk of respiratory depression
- D. Increased risk of bleeding
Correct Answer: B
Rationale: When the proton pump inhibitor is administered with benzodiazepines, there will be a risk for a toxic level of benzodiazepines. When the client is administered sucralfate with the proton pump inhibitor, there will be a decrease in absorption of the proton pump inhibitor. When the client is administered an antacid with opioid analgesics, there will be an increased risk of respiratory depression. There will be an increased risk of bleeding when the client is taking oral anticoagulants with the proton pump inhibitor.
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A nurse is caring for a client who has been prescribed aluminum carbonate gel (Basaljel) for the relief of an acute peptic ulcer. Which of the following interventions should the nurse perform to promote an optimal response to therapy?
- A. Administer the drug hourly for the first 2 weeks.
- B. Administer the drug early in the morning before breakfast.
- C. Administer the drug with 40 mL of apple juice.
- D. Administer the first dose by IV route and then orally.
Correct Answer: A
Rationale: The nurse should administer the drug hourly for the first 2 weeks when treating an acute peptic ulcer. The nurse instructs the client to administer the drug 1 to 2 hours after meals and at bedtime after the first 2 weeks. The nurse need not suggest to the client to administer the drug early to the morning before breakfast nor to administer it with apple juice. The drug is not given intravenously.
A nurse should monitor a client taking which of the following drugs for increased adverse effects and toxicity if omeprazole (Prilosec) therapy is initiated?
- A. Phenobarbital (Luminal)
- B. Digoxin (Lanoxin)
- C. Diazepam (Valium)
- D. Warfarin (Coumadin)
- E. Ketoconazole (Nizoral)
Correct Answer: B,C,D
Rationale: The initiation of proton pump inhibitors, like omeprazole (Prilosec), can result in increased adverse reactions and toxicities of warfarin (Coumadin), benzodiazepines (diazepam), digoxin (Lanoxin), phenytoin (Dilantin), and clarithromycin (Biaxin).
Before administering a prescribed emetic, which of the following would the nurse need to assess?
- A. What chemicals or substances were ingested?
- B. What are the client's current medications?
- C. What time was the substance ingested?
- D. What is the client's blood pressure?
- E. What symptoms were noted before seeking treatment?
Correct Answer: A,C,E
Rationale: Before an emetic is given, it is extremely important to know the chemicals or substances that have been ingested, the time they were ingested, and what symptoms were noted before seeking medical treatment.
A client is diagnosed with an infection with H. pylori. Which of the following drugs are commonly used in combination with certain antibiotics in the treatment of this infection?
- A. Metoclopramide (Reglan)
- B. Omeprazole (Prilosec)
- C. Ondansetron (Zofran)
- D. Lansoprazole (Prevacid)
- E. Promethazine (Phenergan)
Correct Answer: B,D
Rationale: The proton pump inhibitors, like omeprazole (Prilosec) and lansoprazole (Prevacid), are commonly used in combination with certain antibiotics in the treatment of H. pylori.
A nurse educating a client on the antacid magnesium oxide (Mag-Ox) should warn the client of which of the following adverse reactions?
- A. Tremors
- B. Anorexia
- C. Diarrhea
- D. Dehydration
- E. Hypotension
Correct Answer: C,D,E
Rationale: Adverse reactions of magnesium oxide (Mag-Ox) include severe diarrhea, dehydration, and hypermagnesemia (nausea, vomiting, hypotension, and decreased respirations).
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