A nurse is caring for a client who is taking oral Oxycodone The client states he is also taking lbuprofen in three recommended doses daily. The nurse should identify that an interaction between these two medications will cause which of the following findings?
- A. A decrease in serum levels of ibuprofen, possibly leading to a need for increased doses of this medication
- B. A decrease in serum levels of oxycodone, possibly leading to a need for increased doses of this medication
- C. An increase in the expected therapeutic effect of both medications
- D. An increase in expected adverse effects for both medications
Correct Answer: C
Rationale: Both are analgesics; combined use enhances pain relief , a therapeutic synergy, without necessarily increasing adverse effects.
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A nurse is providing teaching for a client who is withdrawing from alcohol and has a new prescription for Propranolol. Which of the following information should the nurse to include in the teaching?
- A. Increases the risk for seizure activity
- B. Provides a form of aversion therapy
- C. Decreases cravings
- D. Results in mild hypertension
Correct Answer: C
Rationale: Propranolol reduces withdrawal symptoms like tremors and cravings , not seizures or aversion.
Which one of the following statements is NOT true of warfarin?
- A. It is extensively 99% bound to plasma albumin
- B. Its use in pregnant women is contraindicated because it is teratogenic
- C. It is active in vitro
- D. Its induced bleeding can be conteracted by treatment with phytonadione
Correct Answer: C
Rationale: Warfarin acts in vivo by inhibiting vitamin K epoxide reductase, not in vitro; thus, is false.
45 year old female has a diabetes mellitus. Endocrinologist prescribes treatment, which has a side effect as hypoglycemia and weight gain. Which of the following drug is prescribed?
- A. Canagliflozin
- B. Exenatide
- C. Gliburide
- D. Pramlintide
Correct Answer: C
Rationale: Gliburide, a sulfonylurea, commonly causes hypoglycemia and weight gain due to increased insulin release.
You are assigned to infuse 300 mL of a solution over 2 hours with a drop factor of 15 gtt/mL. What is the flow rate in drops per minute?
- A. 25 gtt/min
- B. 37.5 gtt/min
- C. 45 gtt/min
- D. 75 gtt/min
Correct Answer: B
Rationale: Flow rate = (300 mL 15 gtt/mL) ÷ (2 60) = 4,500 ÷ 120 = 37.5 gtt/min, exactly matching option B.
A nurse is caring for a client who states she has been taking Phenylephrine nasal drops for the past 10 days for Sinusitis. The nurse should assess the client for which of the following adverse effects of this medication?
- A. Sedation
- B. Nasal congestion
- C. Productive cough
- D. Constipation
Correct Answer: B
Rationale: Prolonged phenylephrine use can cause rebound nasal congestion due to vasoconstrictor overuse.
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