Nokea
Your patient calls for an appointment before going on vacation. Which medication should you ensure he has an adequate supply of before leaving to avoid life-threatening complications?
- A. Carvedilol
- B. Donepezil
- C. Bethanechol
- D. Tacrine
Correct Answer: A
Rationale: Abrupt carvedilol withdrawal can cause life-threatening rebound hypertension or ischemia.
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Identify potential drug-drug interactions that may occur with tamoxifen
- A. Not provided in document
- B. Not provided in document
- C. Not provided in document
- D. Not provided in document
Correct Answer: D
Rationale: This question lacks options in the document, but based on the answer key (ANS: 4), it is assumed to correspond to the fourth choice if options were present. Tamoxifen has significant interactions with CYP2D6 inhibitors (e.g., SSRIs), which can reduce its efficacy.
When prescribing temazepam (Restoril) for insomnia, patient education includes:
- A. Take temazepam nightly approximately 15 minutes before bedtime.
- B. Temazepam should not be used more than three times a week for less than 3 months.
- C. Drinking 1 ounce of alcohol will cause additive effects and the patient will sleep better.
- D. Exercise for at least 30 minutes within 2 hours of bedtime to enhance the effects of temazepam.
Correct Answer: B
Rationale: Temazepam is recommended short-term (e.g., ≤3 times/week) to avoid dependence.
The nurse, providing patient teaching about home medication use to an older adult, explains that even when drugs are taken properly they can produce negative or unexpected effects. What are these negative or unexpected effects called?
- A. Teratogenic effects
- B. Toxic effects
- C. Adverse effects
- D. Therapeutic effects
Correct Answer: C
Rationale: Negative or unexpected effects are known as adverse or side effects. Teratogenic effects are adverse effects on the fetus and not a likely concern for an older adult. Toxic effects occur when medication is taken in larger than recommended dosages caused by an increase in serum drug levels. Therapeutic effects are the desired actions for which the medication is prescribed.
Which one of the following statements is NOT true of warfarin?
- A. It is extensively 99% bound to plasma albumin
- B. Its use in pregnant women is contraindicated because it is teratogenic
- C. It is active in vitro
- D. Its induced bleeding can be conteracted by treatment with phytonadione
Correct Answer: C
Rationale: Warfarin acts in vivo by inhibiting vitamin K epoxide reductase, not in vitro; thus, is false.
What is a prodrug
- A. Drag which increases efficiency of another drug
- B. Metabolic end product
- C. Inactive drag which gets activated in the body
- D. Drag which competes with another for metabolism
Correct Answer: C
Rationale: A prodrug is inactive until metabolized into an active form in the body.