In an acute attack of migraine, the drug of choice is
- A. Ergotamine tartrate
- B. Methysergide
- C. Propranolol
- D. Caffeine
Correct Answer: A
Rationale: Ergotamine tartrate is the drug of choice for acute migraine.
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The nurse, providing patient teaching about home medication use to an older adult, explains that even when drugs are taken properly they can produce negative or unexpected effects. What are these negative or unexpected effects called?
- A. Teratogenic effects
- B. Toxic effects
- C. Adverse effects
- D. Therapeutic effects
Correct Answer: C
Rationale: Negative or unexpected effects are known as adverse or side effects. Teratogenic effects are adverse effects on the fetus and not a likely concern for an older adult. Toxic effects occur when medication is taken in larger than recommended dosages caused by an increase in serum drug levels. Therapeutic effects are the desired actions for which the medication is prescribed.
Please select a correct statement:
- A. Steroids excreted in maximal amount in evening and night time - between 20-24 h
- B. Steroids maximal excretion is in morning time - between -4-8 h
- C. Steroids maximal secretion is in daytime- between -12-16 h
- D. Steroids decrease sensitivity of vessels and bronchus towards catecholamines
Correct Answer: B
Rationale: Steroids peak in the morning (4-8 AM) due to circadian rhythm of cortisol secretion.
The following can be used for diabetes mellitus:
- A. Desmoporesine
- B. Insuline preparations
- C. Chlorpropamide
- D. Metformin
Correct Answer: A
Rationale: Insulin, chlorpropamide, metformin, and acarbose (B, C, D, E) are all used for diabetes management.
Which of the following statement is correct for Amantadine?
- A. Has agonistic action on NDMA type of glutamate receptors
- B. It was developed as antiepileptic drug
- C. Acts as a D2 blocker
- D. Produces livedo reticularis as side effect
Correct Answer: D
Rationale: Amantadine, an antiviral and antiparkinsonian drug, can cause livedo reticularis (a skin mottling side effect); it blocks NMDA receptors, not agonizes them, and enhances dopamine release, not blocks D2.
The NP orders a thyroid panel for a patient on amiodarone. The patient tells the NP that he does not have thyroid disease and wants to know why the test is ordered. Which is a correct response?
- A. Amiodarone inhibits an enzyme that is important in making thyroid hormone and can cause hypothyroidism.
- B. Amiodarone damages the thyroid gland and can result in inflammation of that gland, causing hyperthyroidism.
- C. Amiodarone is a broad-spectrum drug with many adverse effects. Many different tests need to be done before it is given.
- D. Amiodarone can cause corneal deposits in up to 25% of patients.
Correct Answer: A
Rationale: Amiodarone inhibits thyroid hormone synthesis, risking hypothyroidism.
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