Which of the following sign/symptom would NOT be expected from organophosphate poisoning?
- A. Dry skin and mucous membranes
- B. Increased salivation
- C. Increased bowel sounds
- D. Urinary urgency
Correct Answer: A
Rationale: Organophosphates cause wet symptoms (salivation, etc.); dry skin is typical of anticholinergics.
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What is a prodrug
- A. Drag which increases efficiency of another drug
- B. Metabolic end product
- C. Inactive drag which gets activated in the body
- D. Drag which competes with another for metabolism
Correct Answer: C
Rationale: A prodrug is inactive until metabolized into an active form in the body.
In an acute attack of migraine, the drug of choice is
- A. Ergotamine tartrate
- B. Methysergide
- C. Propranolol
- D. Caffeine
Correct Answer: A
Rationale: Ergotamine tartrate is the drug of choice for acute migraine.
Student nurses are learning to weigh patients and do vital signs. How does a correct weight impact administering medication?
- A. Proper dosage calculation
- B. Assessing changes in fluid balance
- C. Assessing changes in nutritional status
- D. Caloric needs
Correct Answer: A
Rationale: Accurate weight is essential for calculating correct medication dosages, especially for weight-based drugs.
Candesartan and irbesartan are angiotensin receptor blockers that are used to treat hypertension. The therapeutic dose range for candesartan is 4 to 32 mg, as compared to 75 to 300 mg for irbesartan. which of the following regarding this statement is correct?
- A. Candesartan is more potent than is irbesartan
- B. Candesartan and irbesartan have different efficacy
- C. Candesartan is a non competitive antagonist for irbesartan
- D. Irbesartan is a competitive antagonist for candesartan
Correct Answer: A
Rationale: Lower dose range for candesartan indicates higher potency (lower EC50) compared to irbesartan.
The nurse, providing patient teaching about home medication use to an older adult, explains that even when drugs are taken properly they can produce negative or unexpected effects. What are these negative or unexpected effects called?
- A. Teratogenic effects
- B. Toxic effects
- C. Adverse effects
- D. Therapeutic effects
Correct Answer: C
Rationale: Negative or unexpected effects are known as adverse or side effects. Teratogenic effects are adverse effects on the fetus and not a likely concern for an older adult. Toxic effects occur when medication is taken in larger than recommended dosages caused by an increase in serum drug levels. Therapeutic effects are the desired actions for which the medication is prescribed.