A nurse is planning caring for a client who is has a new prescription for Torsemide. The nurse should plan to monitor for which of the following adverse reactions of this medications? (Select one that does not apply.)
- A. Respiratory acidosis
- B. Hypokalemia
- C. Hypotension
- D. Ototoxicity
Correct Answer: A
Rationale: Torsemide can cause hypokalemia , hypotension , ototoxicity , and dysrhythmias , typical loop diuretic effects.
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A nurse working for a drug company is involved in phase III drug evaluation studies. Which of the following might the nurse be responsible for during this stage of drug development?
- A. Working with animals who are given experimental drugs
- B. Monitoring drug effects in patients who are selected to participate in a study, who have the disease that the drug is meant to treat
- C. Collecting records of symptoms that participants experience while taking a drug and determining whether they are caused by the disease or the drug
- D. Informing healthy, young volunteer participants of possible risks that could occur from taking an experimental drug
Correct Answer: C
Rationale: Phase III studies involve use of a drug in a vast clinical market where patients are asked to record any symptoms they experience while taking the drugs. Nurses may be responsible for helping collect and analyze the information to be shared with the Food and Drug Administration (FDA). Use of animals in drug testing is done in the preclinical trials. A select group of patients who are involved in phase II studies participate in studies where the participants have the disease the drug is intended to treat. These patients are monitored closely for drug effects. Phase I studies involve healthy human volunteers who are usually paid for their participation. Nurses may observe for adverse effects and toxicity.
Six-year-old Lucy has recently been started on ethosuximide (Zarontin) for seizures. She should be monitored for:
- A. Increased seizure activity, as this drug may auto-induce seizures
- B. Altered renal function, including renal failure
- C. Blood dyscrasias, which are uncommon but possible
- D. Central nervous system excitement, leading to insomnia
Correct Answer: C
Rationale: Ethosuximide can rarely cause blood dyscrasias, requiring monitoring.
Which topical antifungal medication is used to treat vaginal candidiasis?
- A. Haloprogin (Halotex)
- B. Miconazole (Monistat)
- C. Oxiconazole (Oxistat)
- D. Terbinafine HCl (Lamisil)
Correct Answer: B
Rationale: Miconazole is a standard topical treatment for vaginal candidiasis; others target skin infections. Topical miconazole is used to treat vaginal candidiasis.
The treatment of hyperlipidemia with gemfibrozil plus lovastatin is associated with a high risk of:
- A. Constipation
- B. Myopathy
- C. Hepatitis
- D. Thrombocytopenia
Correct Answer: B
Rationale: Combining gemfibrozil and statins increases the risk of myopathy due to elevated statin levels.
Information technology can also be used for patient teaching during the encounter and after it. The provider can help patients and their families become savvy consumers of health-care information by:
- A. Warning them about the questionable quality of health information online
- B. Identifying easily used 'apps' that patients can use to manage their medications
- C. Teaching them how to identify high-quality Web sites and 'red flags' signaling inaccurate content
- D. All of the above
Correct Answer: D
Rationale: All these strategies help patients navigate health information effectively.