Nokea
A nurse is preparing to administer medications to a 4-month-old infant. Which of the following pharmacokinetic principles should the nurse consider when administering medications to this client?
- A. Infants have a more rapid gastric emptying time.
- B. Infants have normal liver function.
- C. Infants have a more rapid gastric emptying time.
- D. Infants have an increased ability to absorb topical medications.
Correct Answer: D
Rationale: Immature liver function affects metabolism, and increased topical absorption occurs due to thinner skin; rapid gastric emptying (A,C) is incorrect.
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An older client recently has been taking cimetidine (Tagamet). The nurse monitors the client for which most frequent central nervous system side effect of this medication?
- A. Tremors
- B. Dizziness
- C. Confusion
- D. Hallucinations
Correct Answer: C
Rationale: Cimetidine is a histamine 2 (H2)-receptor antagonist. Older clients are especially susceptible to central nervous system side effects of cimetidine. The most frequent of these is confusion. Less common central nervous system side effects include headache, dizziness, drowsiness, and hallucinations.
Hypoglycemia can result from the action of either insulin or an oral hypoglycemic. Signs and symptoms of hypoglycemia include:
- A. Fruity' breath odor and rapid respiration
- B. Diarrhea, abdominal pain, weight loss, and hypertension
- C. Dizziness, confusion, diaphoresis, and tachycardia
- D. Easy bruising, palpitations, cardiac dysrhythmias, and coma
Correct Answer: C
Rationale: Hypoglycemia presents with neuroglycopenic (dizziness, confusion) and adrenergic (diaphoresis, tachycardia) symptoms.
When documenting, which of the following would be appropriate for the nurse to use at accredited health care organizations? Select one that does not apply.
- A. IU
- B. 2mg
- C. 0.2 mg
- D. Units
Correct Answer: A
Rationale: Always use a leading zero when writing decimals (i.e., 0.2 mg, not .2 mg) and leave off the trailing zero (i.e., 2 mg, not 2.0 mg). Always write out units, international units, and daily; do not use U, IU, or QD.
A characteristic that distinguishes true receptors from other drug binding sites present in blood and other biological tissues is the characteristic of:
- A. binding affinity
- B. reversible binding
- C. signal transduction
- D. stereoselective interaction
Correct Answer: B
Rationale: Reversible binding is a key feature of true receptors, distinguishing them from non-specific binding sites like plasma proteins.
Which of the following drugs can be used in cases of beta blocker overdose?
- A. Glucagon
- B. Flumazenil
- C. Deferoxamine
- D. Naloxone
Correct Answer: A
Rationale: Glucagon increases cardiac contractility via a non-beta receptor pathway, making it effective in beta-blocker overdose.