A nurse is providing care to a client with a sulfonamide allergy. The nurse would expect to administer which of the following cautiously if prescribed? Select all that apply.
- A. Maraviroc (Selzentry)
- B. Lamivudine (Epivir)
- C. Fosamprenavir (Lexiva)
- D. Ritonavir (Norvir)
- E. Amprenavir (Agenerase)
Correct Answer: C,E
Rationale: If a client has a sulfonamide allergy, the antiretroviral drugs fosamprenavir and amprenavir should be used cautiously.
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An HIV-positive patient on antiretroviral therapy informs the nurse that he is considering taking sildenafil. The nurse informs the patient that he may experience which of the following when taking sildenafil with antiretroviral therapy?
- A. Feching of dizziness
- B. Tching of skin
- C. Risk of hypotension
- D. Depression
- E. Nausea
Correct Answer: C
Rationale: The nurse should educate the patient regarding the associated risks, such as hypotension, visual disturbances, and prolonged penile erection. Feeling of dizziness, itching of skin, depression, and nausea are not conditions that are specifically associated with sildenafil and antiretroviral drugs.
A group of nursing students are reviewing information about antiretroviral therapy. The students demonstrate understanding of the information when they identify which conditions as requiring cautious use of this class of drugs? Select all that apply.
- A. Diabetes
- B. Hemophilia
- C. Impaired hepatic function
- D. Impaired renal function
- E. Hypertension
Correct Answer: A,B,C
Rationale: Antiretroviral drugs should be used cautiously in clients with diabetes, impaired hepatic function, pregnancy, or hemophilia.
A nurse is preparing to administer antiviral therapy. The nurse integrates knowledge of this therapy, administering the drugs cautiously to clients with which of the following? Select all that apply.
- A. Hepatic impairment
- B. Renal impairment
- C. Diabetes
- D. Low blood cell count
- E. Hypertension
Correct Answer: B,D
Rationale: Antivirals should be used cautiously in clients with renal impairment, low blood cell counts, history of epilepsy (rimantadine), and history of respiratory disease (zanamivir).
Antiviral drugs have limited use because they are effective against only a small number of specific viral infections. The nurse would expect antiviral drugs to be used for which infection? Select all that apply.
- A. Human immunodeficiency virus (HIV)
- B. Herpes simplex virus (HSV)
- C. Cytomegalovirus (CMV)
- D. Rotavirus
- E. Rhinovirus
Correct Answer: A,B,C
Rationale: Antiviral drugs are used in the treatment or prevention of infections caused by cytomegalovirus (CMV), herpes simplex virus (HSV) 1 and 2, herpes zoster, human immunodeficiency virus (HIV), influenza A and B, respiratory syncytial virus (RSV), and hepatitis B and C. They are not used for rotavirus or rhinovirus infections.
The nurse is preparing a plan of care for a client being treated with an antiviral drug. Which outcome would the nurse most likely identify? Select all that apply.
- A. Client remains free of other medical conditions.
- B. Client demonstrates an optimal response to therapy.
- C. Client exhibits continual changes in vital signs.
- D. Client demonstrates ability to manage adverse reactions.
- E. Client verbalizes understanding of the therapeutic regimen.
Correct Answer: B,D,E
Rationale: Optimal response to therapy and meeting of client needs related to the management of adverse reactions and an understanding of the therapeutic regimen are outcomes that should be addressed by the nurse in the planning step of the nursing process. Continually changing vital signs would be inappropriate. Remaining free of other medical conditions would be unrealistic.
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