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A nursing instructor asks a student to explain the influence of chronobiology on depression. Which of the following would the student include when responding?
- A. The exact location of genes leads to identifying the gene responsible for causing depression.
- B. A break in the corpus callosum blocks information exchange between the right and left hemispheres.
- C. Damage to the posterior areas of the parietal lobe leads to altered discriminative sensory function.
- D. Internal and external triggers can elicit biologic rhythm changes indicative of clinical depression.
Correct Answer: D
Rationale: Chronobiology studies biological rhythms, such as circadian rhythms, which influence mood disorders like depression. Internal (e.g., hormonal changes) and external (e.g., light exposure) triggers can disrupt these rhythms, contributing to depressive symptoms. The other options relate to genetics, brain connectivity, or sensory function, not chronobiology.
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A nurse is reading a journal article about psychoneuroimmunology. Which information would the nurse most likely find? Select all that apply.
- A. Neurotoxin?s role in receptor site damage
- B. Hypothalamic-pituitary-thyroid axis disruption
- C. Static activity of natural killer cells in response to stress
- D. Hypothalamic damage leading to immune dysfunction
- E. Interruption in the typical circadian rhythm cycle
Correct Answer: B,D,E
Rationale: Psychoneuroimmunology studies interactions between the nervous, endocrine, and immune systems. Hypothalamic-pituitary-thyroid axis disruption (B), hypothalamic damage leading to immune dysfunction (D), and circadian rhythm interruptions (E) are relevant, as they link stress and brain function to immune responses. Neurotoxins (A) are less central, and natural killer cells are not static (C) but increase with stress.
A patient is scheduled for a challenge test. Which of the following would the nurse include when explaining this test to the patient?
- A. Intravenous administration of a substance to induce symptoms
- B. Application of electrodes to the scalp for monitoring
- C. Evaluation electrical impulses recorded on graph paper
- D. Exposure to a flashing strobe light to elicit abnormal activity
Correct Answer: A
Rationale: A challenge test involves administering a substance (e.g., a drug) to provoke symptoms for diagnostic purposes. Electrodes and electrical impulses relate to EEGs, and strobe lights are used in evoked potential tests, not challenge tests.
A nurse is involved in gathering information about the inheritance of mental disorders using population genetics. Which of the following would the nurse be least likely to be evaluating?
- A. Concordance rates
- B. Occurrence in first-degree relatives
- C. Risk factor analysis
- D. Adoptions studies
Correct Answer: C
Rationale: Population genetics studies inheritance patterns using concordance rates, first-degree relative occurrences, and adoption studies to isolate genetic vs. environmental factors. Risk factor analysis, while relevant to epidemiology, is less specific to genetic inheritance studies.
When describing neuronal transmission, an instructor describes the area where the electrical intracellular signal becomes a chemical one. The instructor is describing which of the following?
- A. Soma
- B. Synaptic cleft
- C. Terminal
- D. Receptor site
Correct Answer: B
Rationale: The synaptic cleft is where the electrical signal (action potential) triggers the release of neurotransmitters, converting the signal to a chemical one. The soma is the cell body, the terminal releases neurotransmitters, and the receptor site binds them.
A patient with depression tells the nurse that he is to have a test that involves the recording of an electroencephalogram (EEG) throughout the night. The nurse most likely identifies this testing as which of the following?
- A. Sleep deprivation EEG
- B. Polysomnography
- C. Evoked potentials
- D. Functional magnetic resonance imaging
Correct Answer: B
Rationale: Polysomnography involves overnight EEG recording to assess sleep patterns, often used in depression to evaluate sleep disturbances. Sleep deprivation EEG requires staying awake, evoked potentials test sensory responses, and fMRI measures brain activity, not sleep.