A patient has been receiving a large dose of prednisone for the relief of arthritic pain for 6 months. He suddenly stops taking his medication. What is the most serious concern?
Correct Answer: B
Rationale: The correct answer is B: He will develop an acute adrenal insufficiency. When a patient abruptly stops taking a large dose of prednisone after long-term use, it can suppress the body's natural production of cortisol. This sudden withdrawal can lead to adrenal insufficiency, a potentially life-threatening condition. The adrenal glands may not be able to produce enough cortisol to meet the body's needs, causing symptoms such as fatigue, weakness, low blood pressure, and even shock. This is a serious concern that requires medical attention.
Incorrect choices:
A: His arthritic pain will recur - While this is a valid concern, it is not the most serious issue compared to acute adrenal insufficiency.
C: He will continue to exhibit symptoms of Cushing syndrome - Cushing syndrome is a result of prolonged exposure to high levels of cortisol, not sudden withdrawal.
D: He will develop a moon face and buffalo hump - These are physical symptoms associated with Cushing syndrome, not acute adrenal