Nokea
AH of the following do not cross the blood brain barrier except
- A. Pyridostigmine
- B. Neostigmine
- C. Physostigmine
- D. Ambenonium
Correct Answer: C
Rationale: Physostigmine, a tertiary amine, crosses the blood-brain barrier; others (quaternary amines) do not.
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Which of the following statement is not correct for insulin medications:
- A. Effective for treatment of diabetes type I
- B. Effective for treament of diabetes type II
- C. Is for parenteral use
- D. Is for intravenous use only
Correct Answer: D
Rationale: Insulin is not exclusively for IV use; it's typically subcutaneous, though IV is used in emergencies.
The FDA issued a safety announcement regarding the use of erythropoiesis-stimulating agents (ESAs) in 2010 with the recommendation that:
- A. ESAs no longer be prescribed to patients with chronic renal failure
- B. The risk of tumor development be explained to cancer patients on ESA therapy
- C. Patients should no longer receive ESA therapy to prepare for allogenic transfusions
- D. ESAs be prescribed only to patients staying
Correct Answer: B
Rationale: The 2010 FDA warning highlighted tumor progression risks in cancer patients on ESAs; renal use continues with caution.
The processes involved in dynamic equilibrium are key elements in the nurse's ability to determine what?
- A. Dosage scheduling
- B. Amount of solution for mixing parenteral drugs
- C. Timing of other drugs the patient is taking
- D. How long the patient has to take the drug
Correct Answer: A
Rationale: These processes are key elements in determining the amount of drug (dose) and the frequency of dose repetition (scheduling) required to achieve the critical concentration for the desired length of time. The processes in dynamic equilibrium are not key elements in determining the amount of diluents for intramuscular (IM) drugs; they do not aid in the timing of the other drugs the patient is taking or how long the patient has to take the drug.
A nurse in an acute care facility is caring for a client who is receiving IV Nitroprusside for hypertensive crisis. The nurse should monitor the client for which of the following adverse reactions to this medication?
- A. Intestinal ileus
- B. Neutropenia
- C. Deurium
- D. Hyperthermia
Correct Answer: C
Rationale: Nitroprusside can cause delirium (C, likely typo for delirium), a CNS side effect in toxicity.
The following drugs may precipitate angina pectoris EXCEPT:
- A. Amphetamine
- B. Hydralazine
- C. Isoproterenol
- D. Epinephrine
Correct Answer: D
Rationale: Propranolol, a beta-blocker, relieves angina, unlike the others which increase cardiac demand.