Nokea
Indirect costs associated with drug therapy include:
- A. The cost of diagnostic tests to monitor therapeutic levels
- B. Health-care provider time to prescribe and educate the patient
- C. Child-care expenses incurred while receiving therapy
- D. Loss of wages while undergoing drug therapy
Correct Answer: D
Rationale: Indirect costs include societal impacts like lost wages due to treatment.
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A nurse is instructing a pregnant patient concerning the potential risk to her fetus from a pregnancy category B drug. The nurse would inform the patient that:
- A. Adequate studies in pregnant women have demonstrated there is no risk to the fetus.'
- B. Animal studies have not demonstrated a risk to the fetus but there have been no adequate studies in pregnant women.'
- C. Animal studies have shown an adverse effect on the fetus but there are no adequate studies in pregnant women.'
- D. There is evidence of human fetal risk but the potential benefits from use of the drug may be acceptable despite potential risks.'
Correct Answer: B
Rationale: Category B indicates that animal studies have not demonstrated a risk to the fetus but there have been no adequate studies in pregnant women. However, there have not been adequate studies in pregnant women to demonstrate risk to a fetus during the first trimester of pregnancy and no evidence of risk in later trimesters. Category A indicates that adequate studies in pregnant women have not demonstrated a risk to the fetus in the first trimester or in later trimesters. Category C indicates that animal studies have shown an adverse effect on the fetus but there have been no adequate studies in humans. Category D reveals evidence of human fetal risk, but the potential benefits from the use of the drugs in pregnant women may outweigh the risks.
A nurse is preparing to administer vancomycin 1 g by intermittent IV bolus. Available is vancomycin 1 g in 100 mL of dextrose 5% in water (D5W) to infuse over 45 min. The drop factor of the manual IV tubing is 10 gtt/mL. The nurse should adjust the manual IV infusion to deliver how many gtt/min? (Round the answer to the nearest whole number. Do not use a trailing zero.)
- A. 22
- B. 25
- C. 20
- D. 18
Correct Answer: A
Rationale: Calculation: (100 mL / 45 min) 10 gtt/mL = 22.22, rounded to 22 gtt/min, matching the provided answer.
A nurse is assisting with caring for a client with cancer who is receiving cisplatin. Select the adverse effects that the nurse monitors for that are associated with this medication. (Select one that does not apply.)
- A. Tinnitus
- B. Ototoxicity
- C. Hyperkalemia
- D. Hypomagnesemia
Correct Answer: C
Rationale: Cisplatin is an alkylating medication. Alkylating medications are cell cycle phase-nonspecific medications that affect the synthesis of DNA by causing the cross-linking of DNA to inhibit cell reproduction. Cisplatin may cause ototoxicity, tinnitus, hypokalemia, hypocalcemia, hypomagnesemia, and nephrotoxicity. Amifostine (Ethyol) may be administered before cisplatin to reduce the potential for renal toxicity. Correct answers include: 1 (Tinnitus), 2 (Ototoxicity), 5 (Nephrotoxicity), 6 (Hypomagnesemia).
Anticholinesterase inhibitors are used to treat:
- A. Peptic ulcer disease
- B. Myasthenia gravis
- C. Both 1 and 2
- D. Neither 1 nor 2
Correct Answer: B
Rationale: Anticholinesterases (e.g., pyridostigmine) treat myasthenia gravis by increasing acetylcholine.
What is the correct statement concerning noncompetitive antagonism:
- A. The potency of the drug does not change
- B. the number of receptors able to bind the agonist is affected
- C. by increasing the conc. of the agonist, we cannot overcome the problem
- D. non of the above is wrong
Correct Answer: D
Rationale: All statements are correct: noncompetitive antagonism reduces efficacy (not potency), affects receptor availability, and cannot be overcome by increasing agonist concentration.