Nokea
An overdose of amitriptyline may precipitate all the following adverse effects EXCEPT:
- A. Cardiac arrhythmias
- B. Hypotension
- C. Sedation
- D. Jaundice
Correct Answer: D
Rationale: Amitriptyline overdose does not typically cause jaundice; it causes anticholinergic and cardiac effects.
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A nurse is working as a member of a research team involved in exploring the unique response to drugs each individual displays based on genetic make-up. What is this area of study is called?
- A. Pharmacotherapeutics
- B. Pharmacodynamics
- C. Pharmacoeconomics
- D. Pharmacogenomics
Correct Answer: D
Rationale: Pharmacogenomics is the area of study that includes mapping of the human genome. In the future, medical care and drug regimens may be personally designed based on a patient's unique genetic make-up. Pharmacotherapeutics is the branch of pharmacology that deals with the uses of drugs to treat, prevent, and diagnose disease. Pharmacodynamics involves how a drug affects the body. Pharmacoeconomics includes the costs involved in drug therapy.
Thirty-two units of Humulin insulin is ordered for the patient. The insulin is supplied in a multidose vial that is labeled 100 units/mL. How much insulin would be needed to treat this patient?
- A. 0.032 cc
- B. 0.32 cc
- C. 3.2 cc
- D. 32 cc
Correct Answer: B
Rationale: A cc is equivalent to an mL. There are 100 units in each cc. Divide that amount by 32 units for the answer (0.32 cc).
Half-lives of hydrophilic beta-blockers tend to be longer than their lipophilic counterparts.
- A. TRUE
- B. FALSE
Correct Answer: A
Rationale: Hydrophilic beta-blockers (e.g., atenolol) have longer half-lives due to renal elimination, unlike lipophilic ones (e.g., propranolol) metabolized by the liver.
A 32-year-old female is dehydrated after running a marathon in hot and humid weather. She requires an IV fluid to increase the blood volume and rehydrate the cells. Which one of the following IV fluids would be appropriate for her condition?
- A. Hypertonic crystalloid solution
- B. Isotonic crystalloid solution
- C. Packed red blood cells
- D. Hypotonic crystalloid solution
Correct Answer: B
Rationale: Isotonic solutions (e.g., normal saline) restore volume and hydration without shifting fluids excessively.
A nurse is caring for a client who has a new prescription for Niacin to reduce cholesterol. The nurse should monitor for which of the following findings as an adverse effect of Niacin?(Select one that does not apply.)
- A. Jaundice
- B. Hyperglycemia
- C. Hearing loss
- D. Flushing of the skin
Correct Answer: C
Rationale: Niacin causes hyperglycemia , flushing , and jaundice from liver effects.