BZDs may be used in following situations EXCEPT:
- A. Anaesthesia
- B. Anxiety
- C. Floppy infant syndrome
- D. Epilepsy
Correct Answer: C
Rationale: Benzodiazepines (BZDs) are used in anesthesia, anxiety, and epilepsy, but floppy infant syndrome is a side effect of maternal BZD use, not a condition treated with them.
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An overdose of amitriptyline may precipitate all the following adverse effects EXCEPT:
- A. Cardiac arrhythmias
- B. Hypotension
- C. Sedation
- D. Jaundice
Correct Answer: D
Rationale: Amitriptyline overdose does not typically cause jaundice; it causes anticholinergic and cardiac effects.
Which drug reference contains monographs about virtually every single-entity drug available in the United States and describes therapeutic uses of drugs, including approved and unapproved uses?
- A. Martindale: The Complete Drug Reference
- B. AHFS Drug Information
- C. Drug Reference
- D. Drug Facts and Comparisons
Correct Answer: B
Rationale: AHFS Drug Information contains monographs about virtually every single-entity drug available in the United States and describes therapeutic uses of drugs, including approved and unapproved uses.
The nurse is caring for a client who has a nasogastric tube in place. The client is to receive an oral medication through the tube. Which action by the nurse would be most appropriate? (Select one that does not apply.)
- A. Not diluting liquids prior to administration
- B. Checking the tube for placement
- C. Dissolving crushed tablets in water prior to administration
- D. Flushing the tube with water after drugs are administered
Correct Answer: A
Rationale: Before administration of an oral drug through an NG tube or gastrostomy tube, the nurse should check the tube for placement, dilute and flush liquid drugs through the tube, crush tablets and dissolve them in water before administering them through the tube, and flush the tube with water after the drugs are placed in the tube to clear the tubing completely.
An Investigational New Drug is filed with the U.S. Food and Drug Administration:
- A. When the manufacturer has completed phase III trials
- B. When a new drug is discovered
- C. Prior to animal testing of any new drug entity
- D. Prior to human testing of any new drug entity
Correct Answer: D
Rationale: An IND is filed before human testing , after preclinical (animal) studies, to ensure safety before clinical trials begin.
Food can alter the pH of the stomach, leading to:
- A. Enhanced drug metabolism
- B. Altered vitamin K absorption
- C. Increased vitamin D absorption
- D. Altered drug bioavailability
Correct Answer: D
Rationale: Changes in stomach pH due to food can affect drug dissolution and absorption, altering bioavailability.