Angina pectoris, tachycardia, and arrhythmias are possible adverse effects of which of the following drugs?
- A. Clonidine
- B. Phenylephrine
- C. Propranolol
- D. Salbutamol
Correct Answer: D
Rationale: Salbutamol, a beta-2 agonist, can cause cardiac stimulation as a side effect.
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Prescribers have been shown to override a medication alert about a patient's allergies when:
- A. The history showed that the patient had tolerated the medication in the past
- B. The benefit outweighed the risk
- C. The medication was therapeutically appropriate and needed
- D. All of the above
Correct Answer: D
Rationale: Prescribers may override alerts if past tolerance, benefit-risk balance, or therapeutic need justifies it.
Beta blockers are the drugs of choice for exertional angina because they:
- A. Improve myocardial oxygen supply by vasodilating the coronary arteries
- B. Decrease myocardial oxygen demand by decreasing heart rate and vascular resistance
- C. Both 1 and 2
- D. Neither 1 nor 2
Correct Answer: B
Rationale: Beta blockers reduce oxygen demand by lowering heart rate and resistance, not by vasodilation.
Which statement is not correct about metformin:
- A. Is for internal use only
- B. Reduce weight, apetite
- C. More frequently causes nausea and vomiting comparing with other hypoglicemic drugs
- D. Use for diabetes mellitus type I
Correct Answer: D
Rationale: Metformin is not typically used for type 1 diabetes, which requires insulin, as it acts on insulin sensitivity and hepatic glucose production.
Hepatitis B vaccine is contraindicated in patients who:
- A. Were born after less than 32 weeks gestation (give first dose at age 6 months)
- B. Are pregnant
- C. Are on hemodialysis
- D. Are allergic to yeast
Correct Answer: D
Rationale: Hepatitis B vaccine is contraindicated in yeast allergy (it's yeast-derived); prematurity , pregnancy , or dialysis are not.
Activation of central alpha2 receptors results in inhibition of cardio acceleration and centers in the brain.
- A. Vasodilation
- B. Vasoconstriction
- C. Cardiovascular
- D. Respiratory
Correct Answer: B
Rationale: Alpha2 receptor activation (e.g., by clonidine) causes vasoconstriction and reduced sympathetic outflow.