Carbamazepine has a Black Box Warning due to life-threatening:
- A. Renal toxicity, leading to renal failure
- B. Hepatotoxicity, leading to liver failure
- C. Dermatologic reaction, including Steven's Johnson and toxic epidermal necrolysis
- D. Cardiac effects, including supraventricular tachycardia
Correct Answer: C
Rationale: Carbamazepine's Black Box Warning highlights severe skin reactions like SJS/TEN.
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A nurse working in radiology administers iodine to a patient who is having a computerized axial tomography (CAT) scan. A nurse working on an oncology unit administers chemotherapy to patients who have cancer. At the Public Health Department, a nurse administers a measles-mumps-rubella (MMR) vaccine to a 14month-old child as a routine immunization. Which branch of pharmacology best describes the actions of all three nurses?
- A. Pharmacoeconomics
- B. Pharmacotherapeutics
- C. Pharmacodynamics
- D. Pharmacokinetics
Correct Answer: B
Rationale: Pharmacology is the study of the biologic effects of chemicals. Nurses are involved with clinical pharmacology or pharmacotherapeutics, which is a branch of pharmacology that deals with the uses of drugs to treat, prevent, and diagnose disease. The nurse working in radiology is administering a drug to help diagnose a disease. The nurse working on an oncology unit is administering a drug to help treat a disease. Pharmacoeconomics includes any costs involved in drug therapy. Pharmacodynamics involves how a drug affects the body, and pharmacokinetics is how the body acts on the drug.
A nurse is caring for a hospitalized client who is receiving IV heparin for a deep-vein thrombosis. The client begins vomiting blood. After the heparin has been stopped, which of the following medications should the nurse prepare to administer?
- A. Vitamin k1
- B. Atropine
- C. Protamine
- D. Calcium gluconate
Correct Answer: C
Rationale: Protamine reverses heparin's anticoagulant effect in bleeding emergencies.
When taking a medication history on a patient why should the nurse ask about the use of alternative therapies?
- A. Patients who use new drugs are usually not compliant with medical regimens.
- B. Many drug-alternative therapy interactions can cause serious problems and should be avoided.
- C. Natural products may be more effective and the drug may not be needed.
- D. The cost of the drug and the alternative therapy may be too great for the patient to handle.
Correct Answer: B
Rationale: Alternative therapies can interact with prescribed drugs, potentially causing adverse effects, making this a critical assessment point.
Pharmacogenetic testing is required by the U.S. Food and Drug Administration prior to prescribing:
- A. Erythromycin
- B. Digoxin
- C. Cetuximab
- D. Rifampin
Correct Answer: C
Rationale: FDA requires pharmacogenetic testing for cetuximab to check EGFR status, not for erythromycin, digoxin, or rifampin.
David presents to the clinic with symptoms of allergic conjunctivitis. He is prescribed cromolyn sodium (Opticrom) eye drops. The education regarding using cromolyn eye drops includes:
- A. He should not wear his soft contacts while using the cromolyn eye drops
- B. Cromolyn drops are instilled once a day to prevent allergy symptoms
- C. Long-term use may cause glaucoma
- D. He may experience bradycardia as an adverse effect
Correct Answer: A
Rationale: Cromolyn can irritate soft contacts, requiring removal; it's not once daily or linked to glaucoma .
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