Nokea
Competitive antagonists.
- A. Dissociate from receptors faster than their respective agonists
- B. Alter the shape of the log dose response curve of an agonist
- C. According to the rate theory have low dissociation rate constants
- D. Initiate the opposite cellular response to receptor occupancy to that obtained by the agonist
Correct Answer: C
Rationale: Competitive antagonists have low dissociation rates per rate theory, allowing them to block agonists effectively.
You may also like to solve these questions
The nurse administers an intravenous medication with a half-life of 24 hours but recognizes what factors in this patient could extend the drug's half-life? (Select one that does not apply.)
- A. Gastrointestinal disease
- B. Kidney disease
- C. Liver disease
- D. Cardiovascular disease
Correct Answer: A
Rationale: Kidney disease could slow excretion and extend the drug's half-life. Liver disease could slow metabolism resulting in an extended half-life. Cardiovascular disease could slow distribution resulting in a longer half-life. Gastrointestinal disease would not impact half-life because the medication was injected directly into the bloodstream. Route of administration would not extend half-life because IV injection eliminates the absorption step in the process.
A nurse is preparing to administer a prescribed drug by the oral route. Which of the following would be most important for the nurse to do? Select one that does not apply.
- A. Making sure the client is in an upright position prior to administration
- B. Ensuring that a full glass of water is readily available
- C. Encourage patient to take a few sips of water before placing the medicine in the mouth
- D. Instructing the client to tilt his or her head back to swallow a capsule
Correct Answer: D
Rationale: Clients should always be in an upright position when receiving oral drugs and a glass of water should be readily available. They should be encouraged to take a few sips of water before placing the tablet or capsule in the mouth. Drugs should never be left at the client's bedside. Instruct clients to tilt their head back to swallow a tablet and slightly forward to swallow a capsule.
The nurse is conducting an admission assessment on a patient. When collecting data related to medications the nurse asks, What medications are you currently taking? After collecting this information, what other questions should the nurse ask?
- A. Do you take any medications?
- B. What over-the-counter (OTC) medications do you take?
- C. Do you take gym sessions?
- D. Do you take medications safely when you take them?
Correct Answer: B
Rationale: OTC meds and supplements can affect therapy; 'current medications' already covers A, and D is vague.
In response to the patients question about how to know whether drugs are safe, the nurse explains that all medications undergo rigorous scientific testing controlled by what organization?
- A. Food and Drug Administration (FDA)
- B. Drug Enforcement Agency (DEA)
- C. Centers for Disease Control and Prevention (CDC)
- D. Joint Commission on Accreditation of Healthcare Organizations (JCAHO)
Correct Answer: A
Rationale: The FDA is responsible for controlling and regulating the development and sale of drugs in the United States, allowing new drugs to enter the market only after being subjected to rigorous scientific testing. The DEA regulates and controls the use of controlled substances. The CDC monitors and responds to infectious diseases. The JCAHO is an accrediting body that inspects acute care facilities to ensure minimum standards are met.
A young adult female who is taking metronidazole (Flagyl) to treat trichomoniasis calls the nurse to report severe headache, flushing, palpitations, cramping, and nausea. What will the nurse do next?
- A. Ask about alcohol consumption
- B. Reassure her that these are harmless side effects
- C. Tell her that this signals a worsening of her infection
- D. Tell her to go to the emergency department immediately
Correct Answer: A
Rationale: Metronidazole with alcohol causes a disulfiram-like reaction (symptoms listed); it's not infection worsening or harmless . Patients who are taking metronidazole can experience a disulfiram-like reaction when they drink alcohol.