Questions and Answers on Respiratory System Related

Review Questions and Answers on Respiratory System related questions and content

Foetal hemoglobin has a Sigmoid dissociation curve which is shifted to left relative to adult Hb because

  • A. Foetal Hb has higher P50
  • B. Foetal HB has lower P50 (18-20 mm Hg) than Adult Hb (26.6 mm.Hg)
  • C. Foetal Hb readily accept Oxygen
  • D. Foetal Hb easily remove Carbon dioxide
Correct Answer: B

Rationale: The correct answer is B because foetal Hb has a lower P50 (18-20 mm Hg) than adult Hb (26.6 mm Hg). A lower P50 indicates higher oxygen affinity, allowing foetal Hb to bind oxygen more readily at lower partial pressures. This shift to the left of the dissociation curve ensures efficient oxygen transfer from the maternal bloodstream to the foetus. Choices A, C, and D are incorrect because foetal Hb having a higher P50 (A), readily accepting oxygen (C), or easily removing carbon dioxide (D) would not explain the left shift in the dissociation curve.