Gonadocorticoid(s) ________.
- A. synthesized by the adrenal medulla are primarily androgens
- B. production by the adrenal gland is insignificant compared with sex hormone release from the gonads during late puberty
- C. secretion inhibition is highly dependent on a negative feedback loop involving ACTH
- D. hypersecretion can result in adrenogenital syndrome, also called feminization
Correct Answer: B
Rationale: The correct answer is B because during late puberty, the production of sex hormones by the gonads significantly outweighs the production of gonadocorticoids by the adrenal gland. This is due to the maturation and increased activity of the gonads during this developmental stage.
Rationale:
A: Synthesized by the adrenal medulla are primarily catecholamines, not androgens.
C: Secretion inhibition of gonadocorticoids is primarily regulated by the renin-angiotensin-aldosterone system, not solely by a negative feedback loop involving ACTH.
D: Hypersecretion of gonadocorticoids can lead to conditions like Cushing's syndrome, not adrenogenital syndrome or feminization.
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All of the following are cardiovascular actions of noradrenaline EXCEPT:
- A. Increases systolic blood pressure
- B. Increases diastolic blood pressure
- C. Reflex bradycardia
- D. Constriction of coronary blood vessels
Correct Answer: D
Rationale: Noradrenaline acts on alpha receptors in the cardiovascular system, leading to increased systolic and diastolic blood pressure. It also causes reflex bradycardia by activating baroreceptors. However, noradrenaline does not directly constrict coronary blood vessels, as it primarily acts on alpha receptors and not on coronary vessels. This lack of direct effect on coronary blood vessels is why option D is the correct answer.
Iodine, colloid, and goiter refer to which gland?
- A. Pancreas
- B. Parathyroid
- C. Thyroid
- D. Neurohypophysis
Correct Answer: C
Rationale: The correct answer is C: Thyroid. Iodine is essential for thyroid hormone production. A colloid is a gel-like substance found in the thyroid follicles. Goiter is a condition of thyroid enlargement. The other choices are incorrect because the pancreas (A) produces digestive enzymes and hormones like insulin, the parathyroid (B) regulates calcium levels, and the neurohypophysis (D) is part of the pituitary gland responsible for releasing hormones like vasopressin. Thus, the correct choice is the thyroid gland due to its association with iodine, colloid, and goiter.
Hyperglycemic hyperosmolar nonketotic coma (HHNK) is one complication of diabetes. Symptoms include
- A. hypertension
- B. bradycardia
- C. polyuria
- D. Kussmaul respirations
Correct Answer: C
Rationale: Polyuria is a characteristic symptom of HHNK, along with hyperglycemia and severe dehydration.
In a patient with central diabetes insipidus, what will the administration of ADH during a water deprivation test result in?
- A. Decrease in body weight
- B. Decrease in blood pressure
- C. Increase in urinary output
- D. Increase in urine osmolality
Correct Answer: D
Rationale: In central diabetes insipidus, administering ADH during a water deprivation test will result in an increase in urine osmolality due to the kidneys' ability to concentrate urine in response to ADH.
Which of the following statements regarding hormones is incorrect?
- A. Hormones and neurotransmitters require a synapse in order to communicate information to other cells and tissues.
- B. Only cells that have receptors to a certain hormone may be affected by that hormone.
- C. Hormones can cause target cells to alter patterns of gene expression, producing proteins in different quantities
- D. G proteins and cAMP are second messengers that serve to enhance or amplify the hormonal effect.
Correct Answer: a
Rationale: The correct answer is A because hormones and neurotransmitters do not require a synapse to communicate with other cells. Hormones are typically released into the bloodstream and travel throughout the body to target cells with specific receptors. Neurotransmitters, on the other hand, communicate across synapses between nerve cells. Choice B is correct as hormones only affect cells with specific receptors. Choice C is correct as hormones can indeed influence gene expression in target cells. Choice D is correct as G proteins and cAMP are common second messengers that help transmit the hormonal signal within the cell.