Hormones can be put into two categories based on chemical makeup. What are these categories?
- A. glands and cortex
- B. proteins and carbohydrates
- C. peptides (proteins) and steroids
- D. endocrine and ectocrine
Correct Answer: C
Rationale: The correct answer is C: peptides (proteins) and steroids. Peptides and steroids are the two main categories of hormones based on their chemical makeup. Peptides are made up of amino acids and include proteins, while steroids are derived from cholesterol. This classification is essential because it determines how hormones are synthesized and how they interact with target cells. Glands and cortex (option A) do not represent the chemical makeup of hormones, proteins and carbohydrates (option B) are broad categories that do not specifically address hormone types, and endocrine and ectocrine (option D) refer to different types of glands, not the chemical composition of hormones.
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A patient presents with a tumor of the adrenal gland. It is determined that the levels of renin-angiotensin is low. Which of the following would lead to increased renin-angiotensin levels?
- A. Cushing's syndrome
- B. Secondary hyperaldosteronism
- C. Primary hyperaldosteronism, Conn's syndrome
- D. A and B
Correct Answer: B
Rationale: The correct answer is B: Secondary hyperaldosteronism. In this scenario, the low renin-angiotensin levels indicate a feedback mechanism where the body is trying to compensate for high aldosterone levels. Secondary hyperaldosteronism, which can be caused by conditions like renal artery stenosis or heart failure, leads to increased aldosterone secretion independent of renin levels, resulting in low renin-angiotensin levels.
A: Cushing's syndrome is associated with excess cortisol production, but it does not directly influence renin-angiotensin levels.
C: Primary hyperaldosteronism (Conn's syndrome) is characterized by high aldosterone levels, not low renin-angiotensin levels.
D: Both Cushing's syndrome and secondary hyperaldosteronism do not necessarily occur together, making this option incorrect.
Steatorrhoea occurs with all of the following EXCEPT:
- A. gastrinoma
- B. congenital defect in gastric lipase
- C. ileal disease with failure to reabsorb bile salts
- D. exocrine pancreatic disease
Correct Answer: B
Rationale: The correct answer is B: congenital defect in gastric lipase. Steatorrhoea is the presence of excess fat in the stool due to malabsorption. Gastrinoma (A), ileal disease (C), and exocrine pancreatic disease (D) can all lead to malabsorption of fats resulting in steatorrhoea. However, a congenital defect in gastric lipase does not directly affect fat absorption in the intestines, making it the exception in this scenario.
Cushing syndrome and Addison’s disease are:
- A. forms of chronic adrenal cortical hypofunction.
- B. forms of chronic adrenal cortical hypersecretion.
- C. treated with replacement doses of cortisol (i.e., prednisone).
- D. disorders of the adrenal cortex.
Correct Answer: D
Rationale: The correct answer is D because both Cushing syndrome and Addison's disease are disorders of the adrenal cortex. Cushing syndrome involves excessive cortisol production, while Addison's disease is characterized by insufficient cortisol production. Both conditions directly affect the adrenal cortex, leading to hormonal imbalances.
Choice A is incorrect because Cushing syndrome involves hyperfunction, not hypofunction. Choice B is incorrect as it states hypersecretion, which is true for Cushing syndrome but not for Addison's disease. Choice C is incorrect because while replacement cortisol therapy is used for Addison's disease, it is not the only treatment option, and it does not apply to Cushing syndrome.
A deficiency of insulin causes:
- A. hypocalcemia.
- B. hyperglycemia.
- C. Cushing syndrome.
- D. adrenal shock.
Correct Answer: B
Rationale: The correct answer is B: hyperglycemia. Insulin deficiency leads to an inability to regulate blood sugar levels, resulting in elevated blood glucose levels. Without insulin, glucose cannot enter cells for energy utilization, leading to hyperglycemia. The other choices are incorrect because: A: Hypocalcemia is low calcium levels, not caused by insulin deficiency. C: Cushing syndrome is a hormonal disorder caused by prolonged exposure to high levels of cortisol, not related to insulin deficiency. D: Adrenal shock is a life-threatening condition due to insufficient adrenal gland function, not directly caused by insulin deficiency.
Like the small intestine, the large intestine has villi to aid absorption?
- A. TRUE
- B. FALSE
Correct Answer: B
Rationale: The correct answer is B: FALSE. The large intestine does not have villi like the small intestine. Villi are finger-like projections in the small intestine that increase surface area for nutrient absorption. The large intestine primarily absorbs water and electrolytes, and does not have villi. Other choices are incorrect because the large intestine does not have villi and does not aid in absorption like the small intestine.