Nokea
Hormones produced by the hypothalamus and secreted by the posterior pituitary include:
- A. ADH and aldosterone
- B. ADH and oxytocin
- C. oxytocin and prolactin
- D. cortisol and aldosterone
Correct Answer: B
Rationale: Step 1: The hormones produced by the hypothalamus and secreted by the posterior pituitary are ADH (vasopressin) and oxytocin.
Step 2: ADH regulates water balance by increasing water reabsorption in the kidneys.
Step 3: Oxytocin is involved in uterine contractions during childbirth and milk ejection during breastfeeding.
Step 4: Therefore, choice B (ADH and oxytocin) is correct.
Summary:
- Choice A (ADH and aldosterone) is incorrect because aldosterone is produced by the adrenal glands, not the posterior pituitary.
- Choice C (oxytocin and prolactin) is incorrect because prolactin is produced by the anterior pituitary.
- Choice D (cortisol and aldosterone) is incorrect because cortisol is produced by the adrenal glands, not the posterior pituitary.
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Which of the following drugs has muscarinic and nicotinic actions and is resistant to hydrolysis by both true and pseudo cholinesterase:
- A. Acetylcholine
- B. Carbachol
- C. Bethanechol
- D. Succinylcholine
Correct Answer: B
Rationale: Step-by-step rationale for why B (Carbachol) is the correct answer:
1. Carbachol is a cholinergic drug that acts on both muscarinic and nicotinic receptors.
2. It is resistant to hydrolysis by both true and pseudo cholinesterase enzymes.
3. Acetylcholine (A) is rapidly hydrolyzed by both cholinesterases.
4. Bethanechol (C) is a muscarinic agonist but not a nicotinic agonist.
5. Succinylcholine (D) is a depolarizing neuromuscular blocking agent, not a cholinergic agonist.
Summary:
Carbachol is the only drug among the choices that has both muscarinic and nicotinic actions and is resistant to hydrolysis by cholinesterases. Acetylcholine is rapidly hydrolyzed, Bethanechol does not have nicotinic actions, and Succinyl
The endocrine gland(s) that makes insulin is the:
- A. pancreas
- B. adrenal glands
- C. thyroid gland
- D. pituitary gland
Correct Answer: A
Rationale: The correct answer is A: pancreas. The pancreas is responsible for producing insulin, a hormone that helps regulate blood sugar levels. It is located near the stomach and plays a crucial role in the endocrine system. The other choices (B: adrenal glands, C: thyroid gland, D: pituitary gland) do not produce insulin. Adrenal glands produce hormones like adrenaline and cortisol, thyroid gland produces hormones like thyroxine, and the pituitary gland produces various hormones that regulate other endocrine glands. Therefore, the pancreas is the only gland among the options that produces insulin, making it the correct answer.
Which of the following is not a change that may be caused by hormonal stimulus?
- A. a change in membrane potential
- B. the stimulation of a genetic event resulting in protein synthesis
- C. an increase in enzymatic activity
- D. direct control of the nervous system
Correct Answer: D
Rationale: The correct answer is D: direct control of the nervous system. Hormonal stimuli typically target specific cells or tissues to elicit a response, such as changes in membrane potential, genetic events leading to protein synthesis, or an increase in enzymatic activity. Hormones do not directly control the nervous system, as the nervous system operates independently and responds to its own set of stimuli. Therefore, D is the correct answer as it does not align with the typical effects of hormonal stimulation. Choices A, B, and C are incorrect as they are all changes that can be caused by hormonal stimuli.
The most common second messengers for peptide hormones are ______ and _____.
- A. peptide hormones and calcium.
- B. calcium and glucose.
- C. cAMP and calcium.
- D. cAMP and sodium.
Correct Answer: C
Rationale: The correct answer is C: cAMP and calcium. Peptide hormones bind to their receptors on the cell surface, activating G-proteins which then trigger the production of cAMP as a second messenger. cAMP then further activates protein kinases to initiate various cellular responses. Calcium is also a common second messenger in peptide hormone signaling pathways, regulating processes like muscle contraction and gene expression. Choice A is incorrect because peptide hormones themselves are not second messengers. Choice B is incorrect as glucose is not a common second messenger for peptide hormones. Choice D is incorrect as sodium is not typically involved in peptide hormone signaling pathways.
Which of the following is true about the endocrine system compared to the nervous system?
- A. A single hormone can target many different responses, whereas a nerve only targets a single response.
- B. Blood can carry all the same hormones throughout the body simultaneously, producing responses all over the body; nerve cells can only target a small number of cells.
- C. Nerve cells and blood work together. The endocrine has nothing to do with the nervous system.
- D. Endocrine hormones only target a very small number of precise responses.
Correct Answer: B
Rationale: The correct answer is B because the endocrine system releases hormones into the bloodstream, allowing them to reach all parts of the body simultaneously and produce widespread responses. In contrast, the nervous system sends signals through nerve cells, which can only target a small number of specific cells. This difference in distribution and reach of signals is a key distinction between the endocrine and nervous systems.
Choice A is incorrect because a single hormone can indeed target multiple responses in different parts of the body, similar to how a nerve signal can affect multiple cells along its path.
Choice C is incorrect as nerve cells and the endocrine system can interact and influence each other's functions, such as in the case of stress response involving both systems.
Choice D is incorrect because endocrine hormones can have broad effects on various organs and tissues, not limited to a small number of precise responses.