Hyposecretion of adrenal cortex hormones can lead to ___.
- A. Addison disease.
- B. diabetes mellitus.
- C. Cushing syndrome.
- D. cretinism.
Correct Answer: A
Rationale: The correct answer is A: Addison disease. Hyposecretion of adrenal cortex hormones can lead to Addison disease, characterized by fatigue, weight loss, low blood pressure, and skin discoloration. This is because insufficient cortisol and aldosterone production from the adrenal cortex can disrupt the body's stress response and electrolyte balance.
Summary of why other choices are incorrect:
B: Diabetes mellitus is primarily related to insulin regulation issues, not adrenal cortex hormones.
C: Cushing syndrome is caused by hypersecretion, not hyposecretion, of adrenal cortex hormones.
D: Cretinism is associated with thyroid hormone deficiency, not adrenal cortex hormone deficiency.
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Which of the following is most likely to cause the secretion of calcitonin?
- A. Hypocalcemia
- B. Hyperglycemia
- C. Dehydration
- D. Elevated plasma calcium level
Correct Answer: D
Rationale: The correct answer is D: Elevated plasma calcium level. Calcitonin is released from the thyroid gland in response to high levels of calcium in the blood. When plasma calcium levels are elevated, calcitonin is secreted to help regulate calcium homeostasis by promoting calcium deposition in bones. Choices A, B, and C are incorrect because hypocalcemia (low calcium levels), hyperglycemia (high blood sugar levels), and dehydration do not directly stimulate the secretion of calcitonin.
Donepezil is a reversible anti-cholinesterase used in the treatment of:
- A. Glaucoma
- B. Bradycardia
- C. Urine retention
- D. Alzheimer disease
Correct Answer: D
Rationale: Donepezil is used in the treatment of Alzheimer's disease because it is a reversible anti-cholinesterase that helps improve cognitive function by increasing levels of acetylcholine in the brain. This neurotransmitter is important for memory and learning, which are affected in Alzheimer's disease.
Choice A (Glaucoma) is incorrect because Donepezil does not treat this condition. Choice B (Bradycardia) is incorrect because Donepezil does not affect heart rate. Choice C (Urine retention) is incorrect because Donepezil does not have any impact on urinary function.
In summary, the correct answer is D (Alzheimer's disease) because Donepezil's mechanism of action aligns with the cognitive deficits seen in this condition, while the other choices are not related to the drug's pharmacological effects.
From a medical perspective, ______ hormones can be taken orally because they are water-insoluble lipids and poorly digested.
- A. carbohydrate
- B. peptide
- C. protein
- D. steroid
Correct Answer: D
Rationale: The correct answer is D: steroid. Steroid hormones are lipid-soluble and can pass through cell membranes easily. This property allows them to be taken orally since they are not digested in the stomach and can be absorbed in the intestines. Carbohydrates (A), peptides (B), and proteins (C) are water-soluble and cannot pass through cell membranes easily, making them unsuitable for oral administration.
Which hormone is most important in insulin secretion?
- A. gastrin
- B. CCK
- C. GIP
- D. secretin
Correct Answer: C
Rationale: The correct answer is C: GIP (glucose-dependent insulinotropic peptide). GIP is an incretin hormone released from the small intestine in response to glucose ingestion, stimulating insulin secretion from pancreatic beta cells. Gastrin (A), CCK (B), and secretin (D) are gastrointestinal hormones that do not directly influence insulin secretion. GIP plays a crucial role in regulating blood sugar levels by promoting insulin release, making it the most important hormone in insulin secretion.
Target cells respond to hormones because ____________.
- A. they sit next to the cell that makes the hormone
- B. they made the hormone they are responding to
- C. they have receptors for that hormone
- D. all cells in the body respond to all hormones
Correct Answer: C
Rationale: The correct answer is C because target cells respond to hormones by possessing specific receptors for that hormone. These receptors bind to the hormone, initiating a cellular response. Option A is incorrect as proximity to hormone-producing cells is not the reason for response. Option B is incorrect as target cells do not make the hormones they respond to. Option D is incorrect as not all cells respond to all hormones; only target cells with specific receptors do.