Nokea
In post menopausal women who are receiving estrogen replacement therapy, medroxyprogesterone is administered concurrently to reduce the risk of:
- A. Atherosclerosis
- B. Endometrial cancer
- C. Hypertension
- D. Osteoporosis
Correct Answer: B
Rationale: Progestins like medroxyprogesterone reduce estrogen-induced endometrial hyperplasia and cancer risk.
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Which of the following medications is classified as a Class IA antiarrhythmic?
- A. Amiodarone
- B. Quinidine
- C. Sotalol
- D. Diltiazem
Correct Answer: B
Rationale: Quinidine is a Class IA antiarrhythmic, blocking sodium channels and prolonging the action potential.
Which of the following are poorly perfused tissues?
- A. Heart
- B. Brain
- C. Liver
- D. Kidneys
Correct Answer: B
Rationale: This appears to be a trick question; heart, brain, liver, and kidneys are well-perfused. Assuming intent was poorly perfused, none fit, but B (Brain) is least correct here as it's well-perfused.
Which of the following names may be assigned to a drug during the process of development? (Select one that does not apply.)
- A. Chemical name
- B. Official name
- C. Pharmacologic name
- D. Trade name
Correct Answer: C
Rationale: Throughout the process of development, drugs may have several names assigned to them including a chemical name, a generic (nonproprietary) name, an official name, and a trade or brand name.
A nurse is caring for a client who has a new prescription for Valproic Acid. The nurse should instruct the client that while taking this medication he will need to have which of the following laboratory tests completed periodically?
- A. Thrombocyte count
- B. Hematocrit
- C. Amylase
- D. Kidney function tests
Correct Answer: A
Rationale: Valproic acid requires monitoring of platelets for bleeding risk and liver function for hepatotoxicity.
In which of the following patients would a nurse expect to see an alteration in drug metabolism?
- A. A 35-year-old female with cervical cancer
- B. A 41-year-old male with kidney stones
- C. A 50-year-old male with cirrhosis of the liver
- D. A 62-year-old female in acute renal failure
Correct Answer: C
Rationale: The liver is the most important site of drug metabolism. If the liver is not functioning effectively, as in patients with cirrhosis, drugs will not be metabolized normally and toxic levels could develop. In cirrhosis patients the drug dosage will need to be altered to ensure normal levels in the body.