Which of the following is an adverse event of glucocorticoids:
- A. Osteoporosis
- B. Hypo acid gastritis
- C. Diabetes insipidus
- D. Dehidratation
Correct Answer: A
Rationale: Osteoporosis is a common adverse effect of glucocorticoids due to bone catabolism.
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In which of the following patients would a nurse expect to see an alteration in drug metabolism?
- A. A 35-year-old female with cervical cancer
- B. A 41-year-old male with kidney stones
- C. A 50-year-old male with cirrhosis of the liver
- D. A 62-year-old female in acute renal failure
Correct Answer: C
Rationale: The liver is the most important site of drug metabolism. If the liver is not functioning effectively, as in patients with cirrhosis, drugs will not be metabolized normally and toxic levels could develop. In cirrhosis patients the drug dosage will need to be altered to ensure normal levels in the body.
A nurse is caring for a 77-year-old patient. The nurse would know that a normal physiologic change that must be considered when planning drug therapy, and is associated with aging is what?
- A. Blood volume decreases
- B. Subcutaneous tissue increases
- C. Total body water increases
- D. Muscle mass increases
Correct Answer: A
Rationale: Aging reduces blood volume, altering drug distribution and requiring dosage adjustments.
The American Heart Association and the American Dietetic Association recommend a minimum daily fiber intake of for cardiovascular health:
- A. 10 mg/day
- B. 15 mg/day
- C. 20 mg/day
- D. 25 mg/day
Correct Answer: D
Rationale: 25 g/day of fiber is recommended to reduce cardiovascular risk by lowering cholesterol and improving glucose control.
Laboratory monitoring for patients on angiotensin-converting enzyme inhibitors or angiotensin II receptor blockers should include:
- A. White blood cell counts with the drug dosage increased for elevations above 10,000 feet
- B. Liver function tests with the drug dosage stopped for alanine aminotransferase values twice that of normal
- C. Serum creatinine levels with the drug dosage reduced for values greater than 2.5 mg/dL
- D. Serum glucose levels with the drug dosage increased for levels greater than 120 mg/dL
Correct Answer: C
Rationale: Elevated creatinine (>2.5 mg/dL) indicates renal impairment, requiring dose adjustment.
The standard dosage of St John's wort for the treatment of mild depression is:
- A. 300 mg daily
- B. 100 mg three times a day
- C. 300 mg three times a day
- D. 600 mg three times a day
Correct Answer: C
Rationale: 300 mg three times daily is the standard dose for St John's wort in mild depression.
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