Nokea
Which of the following is an adverse event of glucocorticoids:
- A. Arterial hypotension
- B. Hyponatremia
- C. Hypoglicemia
- D. Facilitate the development of infections
Correct Answer: D
Rationale: Glucocorticoids suppress immunity, increasing infection risk due to reduced inflammatory and immune responses.
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The following relationship exist adrenal steroidal hormones, corticotropin and hypothalamic hormones.
- A. Short direct connection
- B. Long direct connection
- C. Short negative feedback
- D. Long negative feedback
Correct Answer: D
Rationale: Adrenal steroids, corticotropin (ACTH), and hypothalamic CRH form a long negative feedback loop in the HPA axis.
The elderly are at high risk of ADRs due to:
- A. Having greater muscle mass than younger adults, leading to higher volume of distribution
- B. The extensive studies that have been conducted on drug safety in this age group
- C. The blood-brain barrier being less permeable, requiring higher doses to achieve therapeutic effect
- D. Age-related decrease in renal function
Correct Answer: D
Rationale: Age-related renal decline slows drug clearance, raising ADR risk in the elderly, unlike muscle mass , studies , or BBB .
The standard dosage of St John's wort for the treatment of mild depression is:
- A. 300 mg daily
- B. 100 mg three times a day
- C. 300 mg three times a day
- D. 600 mg three times a day
Correct Answer: C
Rationale: 300 mg three times daily is the standard dose for St John's wort in mild depression.
When the costs of a specific treatment or intervention are calculated and then compared with the dollar value of the benefit received it is referred to as:
- A. Cost-minimization analysis
- B. Cost-of-illness analysis
- C. Cost-effectiveness analysis
- D. Cost-benefit analysis
Correct Answer: D
Rationale: Cost-benefit analysis quantifies both costs and benefits in monetary terms.
A nurse is teaching a client who has Graves' disease about her prescribed medications. Which of the following statements by the client indicates an understanding of the use of Propranolol in the treatment of Graves' disease?
- A. Propranolol helps increase blood flow to my thyroid gland.
- B. Propranolol is used to prevent excess glucose in my blood.
- C. Propranolol will decrease my tremors and fast heart beat.
- D. Propranolol promotes a decrease of thyroid hormone in my body
Correct Answer: C
Rationale: Propranolol reduces tremors and tachycardia in Graves' disease by blocking beta-adrenergic effects.