Nokea
L-Dopa is
- A. Converted to methyl dopa in the body
- B. Antagonised by riboflavine
- C. Antagonized by nicotinic acid
- D. Combined with carbidopa for enhanced effect
Correct Answer: D
Rationale: Carbidopa enhances L-Dopa's effect by preventing peripheral breakdown.
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Common side effect of isoniazide:
- A. Hepatitis
- B. Ototoxicity
- C. Visual toxicity
- D. Hepatitis
Correct Answer: A
Rationale: Isoniazid (likely misspelled as Isoniazide) commonly causes hepatitis as a side effect due to its hepatotoxic potential, requiring liver function monitoring. Note: Option D repeats 'Hepatitis,' but A is intended.
Which of the following is not hypoglicemic mechanism of action of metformin?
- A. Enhance insulin release by pancreatic beta cells
- B. Increase cell permeability of glucose and utilisation
- C. Decrease gluconeogenesis
- D. Interfere carbohydrate absorption in the gut
Correct Answer: A
Rationale: Metformin does not enhance insulin release; it improves insulin sensitivity and reduces hepatic glucose production.
The physician has asked a nurse to administer a drug intravenously to a patient who is unresponsive. How can the nurse ensure that the drug is administered to the right patient?
- A. By waking him up to ask him his name
- B. By identifying the patient's room number
- C. By checking the patient's wristband
- D. By asking the nursing assistant for the patient's location
Correct Answer: C
Rationale: The nurse should identify a patient by checking his wristband, which has the patient's name. The nurse should not ask the patient to confirm his name, because some patients, particularly those who are confused or have difficulty hearing, may respond by answering yes. Additionally, this patient is unresponsive. The nurse can obtain the patient's location by asking any other member of the health care staff, but should verify the patient's identity by checking the wristband. The nurse should not rely on the patient's room number alone.
Which of the following is a disadvantage of IM administration?
- A. Larger volumes can be used
- B. Can affect lab tests
- C. Painful
- D. B and C
Correct Answer: C
Rationale: Intramuscular (IM) administration is painful due to needle insertion, though larger volumes are an advantage; affecting lab tests is less specific, making C the primary disadvantage.
Drugs which increase GABA levels in brain
- A. Diazepam
- B. Phenobarbitone
- C. Sodium valproate
- D. Carbamazepine
Correct Answer: C
Rationale: Sodium valproate increases GABA levels.