Medication orders are written with very specific criteria and coincide with the 7 rights of medication administration. What critical piece of information is missing from the following medication order? Amoxicillin 250 mg every 8 hours.
- A. Dose
- B. Route
- C. Frequency of administration
- D. Trade name of the drug
Correct Answer: B
Rationale: The route (e.g., oral, IV) is missing, essential for safe administration per the 7 rights.
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Which of the following is a thiazolidinediones:
- A. Pioglitazone
- B. Exenatide
- C. Sitagliptine
- D. Chlorpropamide
Correct Answer: A
Rationale: Pioglitazone is a thiazolidinedione that enhances insulin sensitivity via PPAR-gamma.
An order is written for a patient to receive 1000 mL of normal saline IV over 8 hours. If the IV infusion set is a microdrip set that delivers 60 drops/mL, how many drops per minute should the patient be receiving?
- A. 60 drops/min
- B. 120 drops/min
- C. 240 drops/min
- D. 480 drops/min
Correct Answer: B
Rationale: If a patient were to receive 1000 mL in 8 hours, dividing 1000 by 8 would mean that the patient would receive 125 mL in 1 hour, or 60 minutes. Setting up the equation, 60 drops/mL X = 125 mL/60 min, and cross-multiplying, the answer is 120 drops/min.
Carvedilol is heavily metabolized by CYP2D6 and 2C9, resulting in drug interactions with which of the following drug classes?
- A. Histamine 2 blockers
- B. Quinolones
- C. Serotonin re-uptake inhibitors
- D. All of the above
Correct Answer: C
Rationale: SSRIs inhibit CYP2D6, increasing carvedilol levels and effects.
Niaspan is less likely to cause which side effect that is common to niacin?
- A. Gastrointestinal irritation
- B. Cutaneous flushing
- C. Dehydration
- D. Headaches
Correct Answer: B
Rationale: Niaspan's extended-release form reduces flushing compared to immediate-release niacin.
A nurse is caring for a client who has increased intracranial pressure and is receiving Mannitol. Which of the following findings should the nurse report to the provider?
- A. Blood glucose 150 mg/dL
- B. Urine output 40 mL/hr
- C. Dyspnea
- D. Bilateral equal pupil size
Correct Answer: C
Rationale: Dyspnea may indicate pulmonary edema, a potential complication of mannitol therapy.