Nokea
Not an antidepressant
- A. Amitryptilline
- B. Fluoxetin
- C. Trazodone
- D. Pimozide
Correct Answer: D
Rationale: Pimozide is an antipsychotic, not an antidepressant.
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One major drug used to treat bipolar disease is lithium. Because lithium has a narrow therapeutic range, it is important to recognize symptoms of toxicity, such as:
- A. Orthostatic hypotension
- B. Agitation and irritability
- C. Drowsiness and nausea
- D. Painful urination and abdominal distention
Correct Answer: C
Rationale: Lithium toxicity commonly presents with drowsiness and nausea.
Up to 21% of Asians are ultra-rapid 2D6 metabolizers, requiring:
- A. A need to monitor drugs metabolized by 2D6 for toxicity
- B. Increased dosages needed of drugs metabolized by 2D6, such as the selective serotonin reuptake inhibitors
- C. Decreased conversion of codeine to morphine by CYP 2D6
- D. The need for lowered dosages of drugs, such as beta blockers
Correct Answer: B
Rationale: Ultra-rapid 2D6 metabolizers (e.g., in Asians) need higher SSRI doses due to fast metabolism, unlike toxicity , codeine issues , or lower doses .
You are to infuse 1,200 mL of IV fluid over 6 hours using a drop factor of 10 gtt/mL. What is the flow rate in drops per minute?
- A. 30 gtt/min
- B. 33 gtt/min
- C. 40 gtt/min
- D. 50 gtt/min
Correct Answer: B
Rationale: Flow rate = (1,200 mL 10 gtt/mL) ÷ (6 60) = 12,000 ÷ 360 = 33.33 gtt/min, rounded to 33 gtt/min.
The mean weight of 500 college students is 70 kg and the standard deviation is 3 kg. Assuming that the weight is normally distributed, determine how many students weigh 64 kg or less.
- A. 5
- B. 11
- C. 15
- D. 20
Correct Answer: B
Rationale: P(X ≤ 64) equals P(X < 64) in a continuous distribution since P(X=64) = 0. From the previous calculation, P(Z < -2) ≈ 0.0228, so 0.0228 * 500 ≈ 11, consistent with the document.
As an antacid, sodium bicarbonate has the following disadvantages EXCEPT:
- A. It causes acid rebound
- B. In ulcer patients, it increases risk of perforation
- C. It has low acid neutralizing capacity
- D. It is contraindicated in CHF
Correct Answer: C
Rationale: Sodium bicarbonate has high acid-neutralizing capacity, but it causes acid rebound, risks perforation in ulcers due to gas production, and is contraindicated in CHF due to sodium load.