NSAIDs combat fever by inhibiting which prostaglandin?
- A. Prostaglandin E2
- B. Prostaglandin I2
- C. Prostaglandin D2
- D. Prostaglandin F2
Correct Answer: A
Rationale: Prostaglandin E2 mediates fever in the hypothalamus; NSAIDs reduce fever by inhibiting its synthesis.
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A patient taking an oral diuretic for about six (6) months presents with elevated fasting and post prandial blood glucose levels. You suspect the glycemic problems are diuretic induced. What is the most likely cause?
- A. Acetazolamide
- B. Amiloride
- C. Chlorothiazide
- D. Spironolactone
Correct Answer: C
Rationale: Thiazides like chlorothiazide impair glucose tolerance by reducing insulin sensitivity.
A nurse is caring for a client who is receiving daily doses of Oprelvekin. Which of the following laboratory values should the nurse monitor to determine effectiveness of this medication?
- A. Hemoglobin
- B. Absolute neutrophil count
- C. Platelet count
- D. Total white blood count
Correct Answer: C
Rationale: Oprelvekin increases platelet count , its primary therapeutic effect.
The following are recognized effects of propranolol except
- A. Increases microcoronary blood flow
- B. Decrease in heart rate
- C. Decrease in cardiac output
- D. Reduction in ventricular systolic pressure
Correct Answer: A
Rationale: Propranolol reduces coronary flow; other effects are correct.
Slow channel syndrome is due to
- A. Accumulation of Na+ ions in channels
- B. Accumulation of K+ ions in channels
- C. Accumulation of Mg++ ions in channels
- D. Accumulation of Ca++ ions in channels
Correct Answer: D
Rationale: Slow channel syndrome relates to calcium channel dysfunction.
Education of patients who are taking warfarin includes discussing their diet. Instructions include:
- A. Avoiding all vitamin K-containing foods
- B. Avoiding high-vitamin K-containing foods
- C. Increasing intake of iron-containing foods
- D. Making sure they eat 35 grams of fiber daily
Correct Answer: B
Rationale: High vitamin K foods antagonize warfarin; total avoidance is unnecessary, and iron or fiber aren't relevant.