Endocrine System MCQ Questions Related

Review Endocrine System MCQ Questions related questions and content

Regarding fat metabolism, which statement is CORRECT?

  • A. ketone bodies accumulate in DKA due to a lack of acetyl-CoA substrate
  • B. fatty acids are transported in the plasma bound to lipoprotein complexes
  • C. cholesterol is transported from extra-hepatic cells to the liver by high-density lipoproteins (HDLs) in the endogenous pathway
  • D. eicosanoids are synthesised from cholesterol
Correct Answer: C

Rationale: The correct answer is C because cholesterol is transported from extra-hepatic cells to the liver by high-density lipoproteins (HDLs) in the endogenous pathway. HDLs are responsible for picking up excess cholesterol from peripheral tissues and transporting it back to the liver for excretion. This process helps regulate cholesterol levels in the body.

Explanation for other choices:
A: Ketone bodies accumulate in DKA due to increased fatty acid breakdown, not a lack of acetyl-CoA substrate.
B: Fatty acids are primarily transported in the bloodstream bound to albumin, not lipoprotein complexes.
D: Eicosanoids are derived from arachidonic acid, not cholesterol.