Nokea
Review of a patient's chart reveals that two years ago she was treated with ritodrine. Which of the following was the most likely condition or reason for which this drug was given?
- A. Parkinson's disease
- B. Bronchial asthma
- C. Depression
- D. Premature labor
Correct Answer: D
Rationale: The correct answer is D: Premature labor. Ritodrine is a tocolytic agent commonly used to inhibit premature labor by relaxing the uterine muscles. It works by decreasing the frequency and intensity of contractions, helping to delay premature delivery. Parkinson's disease (A), bronchial asthma (B), and depression (C) are not conditions typically treated with ritodrine. Parkinson's disease is a neurological disorder, bronchial asthma is a respiratory condition, and depression is a mental health condition. Therefore, based on the pharmacological action of ritodrine and the context of its usage, the most likely reason for which this drug was given in this case is to manage premature labor.
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Giving a single IV injection of phenylephrine can be used to normalize a rapid heart rate in paroxysmal supraventricular tachycardia (PSVT). How does phenylephrine do this?
- A. It blocks the beta-receptors on the heart
- B. It stimulates norepinephrine release from sympathetic nerves to the heart
- C. It raises blood pressure, slowing the heart via the baroreceptor reflex
- D. It stimulates ACh esterase at parasympathetic nerves to the heart
Correct Answer: C
Rationale: Correct Answer: C
Rationale:
1. Phenylephrine is a vasoconstrictor that raises blood pressure.
2. Increased blood pressure activates the baroreceptor reflex.
3. Baroreceptor reflex detects elevated blood pressure and sends signals to the brain.
4. The brain then signals the heart to slow down, thus normalizing the rapid heart rate in PSVT.
Summary:
A: Blocking beta-receptors would have the opposite effect, as beta-blockers slow down the heart rate.
B: Stimulating norepinephrine release would increase heart rate, not slow it down.
D: ACh esterase is involved in the breakdown of acetylcholine, not relevant to the mechanism of action of phenylephrine in PSVT.
Which hormones are produced by the posterior pituitary?
- A. oxytocin and antidiuretic hormone
- B. human growth hormone and thyroid-stimulating hormone
- C. prolactin and follicle-stimulating hormone
- D. glucocorticoids and androgens
Correct Answer: A
Rationale: The correct answer is A: oxytocin and antidiuretic hormone. The posterior pituitary stores and releases these hormones, which are produced in the hypothalamus. Oxytocin is involved in uterine contractions and milk ejection, while antidiuretic hormone regulates water balance. Choices B, C, and D are incorrect because human growth hormone and thyroid-stimulating hormone are produced by the anterior pituitary, prolactin and follicle-stimulating hormone are produced by the anterior pituitary, and glucocorticoids and androgens are produced by the adrenal glands, respectively.
How do hormones differ from neurotransmitters?
- A. Hormones travel through the synaptic cleft while neurotransmitters travel through the bloodstream.
- B. Hormones act on receptors while neurotransmitters do not.
- C. Hormones use speedy electrical impulses, while neurotransmitters take several seconds from the gland to the target tissue.
- D. Hormones travel through the bloodstream while neurotransmitters travel across the synaptic cleft between neurons.
Correct Answer: D
Rationale: The correct answer is D. Hormones travel through the bloodstream while neurotransmitters travel across the synaptic cleft between neurons. Hormones are secreted by endocrine glands into the bloodstream to target distant tissues, while neurotransmitters are released by neurons into the synaptic cleft to transmit signals locally between neurons. Choice A is incorrect as hormones do not travel through the synaptic cleft, and neurotransmitters do not travel through the bloodstream. Choice B is incorrect as both hormones and neurotransmitters act on specific receptors. Choice C is incorrect as hormones do not use electrical impulses; instead, they travel through the bloodstream.
Why is the posterior pituitary gland called the neurohypophysis?
- A. The posterior pituitary gland is an extension of the hypothalamus.
- B. The neurohypophysis secretes releasing hormones.
- C. The posterior pituitary gland secretes hormones that regulate adenohypophyseal function.
- D. The posterior pituitary gland secretes releasing hormones.
Correct Answer: A
Rationale: The correct answer is A because the posterior pituitary gland is an extension of the hypothalamus. The hypothalamus produces hormones that are stored and released by the posterior pituitary gland. This connection between the two structures allows for direct neural control over hormone release.
Option B is incorrect because the neurohypophysis does not secrete releasing hormones; rather, it releases hormones produced by the hypothalamus. Option C is incorrect because the posterior pituitary gland does not regulate adenohypophyseal function; instead, it stores and releases hormones produced by the hypothalamus. Option D is incorrect because the posterior pituitary gland does not secrete releasing hormones; it releases hormones produced by the hypothalamus.
Mr. R, a 52-year-old patient with hyperthyroidism, is experiencing a thyroid storm. Which of the following symptoms would indicate the need for immediate intervention?
- A. Hypothermia
- B. Low blood pressure
- C. Severe tachycardia
- D. Weight gain
Correct Answer: C
Rationale: Severe tachycardia is a hallmark of thyroid storm and requires immediate intervention to prevent life-threatening complications such as heart failure or stroke.