Nokea
(+) ssRNA viruses that have been isolated from birds, cats, dogs, pigs, sheep, cows, and humans and are a major cause of gastroenteritis are the:
- A. rotaviruses
- B. caliciviruses
- C. adenoviruses
- D. noroviruses
Correct Answer: B
Rationale: The correct answer is B: caliciviruses. Caliciviruses are known to be (+) ssRNA viruses that cause gastroenteritis in a wide range of animals, including birds, cats, dogs, pigs, sheep, cows, and humans. These viruses are highly contagious and can spread through contaminated food or water. Rotaviruses (A) are also a common cause of gastroenteritis, but they are not exclusively isolated from the mentioned animals. Adenoviruses (C) typically cause respiratory or eye infections, not gastroenteritis. Noroviruses (D) are also a major cause of gastroenteritis in humans, but they are not commonly found in animals other than humans.
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During fibergastroscopy a patient with ulcer disease of the stomach, the mucosal biopsy is taken from the area of an ulcer. Impression smear is prepared from biopsy material and stained by Gram method; the rest of biopsy material is tested for urease activity. Microscopy of the impression smear revealed gram- negative spiral-shaped microorganisms, urease activity test is positive. What bacteria were detected?
- A. Helicobacter pylori
- B. Campilobacter jejuni
- C. Treponema pallidum
- D. Spirilla minor
Correct Answer: A
Rationale: The correct answer is A: Helicobacter pylori.
Rationale:
1. Gram-negative spiral-shaped microorganisms match the morphology of Helicobacter pylori.
2. Positive urease activity is a characteristic feature of Helicjsonacter pylori.
3. Helicobacter pylori is specifically associated with gastric ulcers and is a common pathogen in the gastrointestinal tract.
Summary:
Choice B, Campilobacter jejuni, is a gram-negative curved bacterium but is not typically associated with gastric ulcers or urease activity. Choice C, Treponema pallidum, is a spirochete bacterium causing syphilis, which is not related to gastric ulcers. Choice D, Spirilla minor, is a generic term for spiral-shaped bacteria and is not a specific pathogen associated with gastric ulcers or urease activity.
A 70-year-old man has developed prosphetic stomatitis. Apart of this he was found to have an evident lesion of mouth corners. Microscopical examination revealed large ovoid gram-positive cells. What microorganisms are most likely to be the leading etiological agent of such a lesion?
- A. Candida fungi
- B. Streptococci
- C. Staphylococci
- D. Neisseria
Correct Answer: A
Rationale: The correct answer is A: Candida fungi. In the context of a 70-year-old man with angular cheilitis (lesion at the corners of the mouth) and stomatitis, the presence of large ovoid gram-positive cells points towards Candida species, which are yeast fungi. Candida is a common opportunistic pathogen that can cause oral thrush and angular cheilitis in immunocompromised individuals, such as elderly people. Candida fungi are known to appear as large ovoid cells under microscopic examination.
Summary of other choices:
B: Streptococci are gram-positive bacteria and are not typically associated with large ovoid cells seen in this case.
C: Staphylococci are also gram-positive bacteria and are not known to present as large ovoid cells in this context.
D: Neisseria are gram-negative bacteria and are not the usual etiological agents for oral lesions like angular cheilitis.
Which of the following viruses belongs to family Caliciviridae?
- A. Norwalk Virus
- B. Yellow fever virus
- C. Rubella virus
- D. CMV
Correct Answer: A
Rationale: The correct answer is A: Norwalk Virus. The Norwalk Virus belongs to the family Caliciviridae because it has characteristic features such as a nonenveloped, single-stranded RNA genome. The other options, Yellow fever virus, Rubella virus, and CMV, belong to different virus families and have distinct characteristics that differentiate them from Caliciviridae. Yellow fever virus is a Flavivirus, Rubella virus belongs to Togaviridae, and CMV is a member of the Herpesviridae family. Therefore, based on the genomic and structural characteristics of the Norwalk Virus, it is the correct choice for belonging to the Caliciviridae family.
A dentist has detected symptoms of parodontosis in a patient. What antiprotozoal drug should be prescribed?
- A. Metronidazole
- B. Levamisole
- C. Griseofulvin
- D. Mykoseptin
Correct Answer: A
Rationale: The correct answer is A: Metronidazole. Parodontosis is a condition caused by bacterial infection, not protozoal infection. Metronidazole is an effective antibiotic commonly used to treat bacterial infections in the oral cavity, including those associated with parodontosis. Levamisole is an anthelmintic drug used to treat parasitic worm infections, not suitable for parodontosis. Griseofulvin is an antifungal medication used for fungal infections, not indicated for parodontosis. Mykoseptin is not a recognized drug and is likely a distractor. Therefore, based on the bacterial nature of parodontosis, Metronidazole is the appropriate choice.
Sanitary bacteriological research on water by the membrane filter method revealed two red colonies on a membrane filter (Endo agar) through which 500 ml of analyzed water were passed. Calculate the coli index and coli titer of the analyzed water:
- A. 4 and 250
- B. 2 and 500
- C. 250 and 4
- D. 500 and 2
Correct Answer: A
Rationale: The correct answer is A: 4 and 250. Coli index is calculated by dividing the number of red colonies by the volume of water analyzed, which gives 2 red colonies / 500 ml = 4. Coli titer is the reciprocal of the coli index, so it is 1 / 4 = 250. This indicates the concentration of coliform bacteria in the water sample. Choices B, C, and D are incorrect as they do not follow the correct calculation steps for determining the coli index and coli titer. B has the correct coli index but incorrect coli titer. C and D have the values reversed, leading to incorrect results.