Nokea
The drug, which interferes with metabolism of theophylline
- A. Gentamicin
- B. Penicillin
- C. Erythromycin
- D. Sulfonamide
Correct Answer: C
Rationale: Erythromycin inhibits cytochrome P-450, reducing theophylline metabolism.
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B-Blockers are contra indicated in
- A. Hypertension
- B. Congestive cardiac failure
- C. Anxiety states
- D. Hyperthyroidis m
Correct Answer: B
Rationale: Beta-blockers worsen congestive heart failure.
The pharmacology students are learning about antibiotics that are known to cause photosensitivity in some patients. What nursing measures would ensure the comfort of patients taking these antibiotics and hopefully avoid serious adverse effects?
- A. Avoiding the use of aspirin and other over-the-counter pain products
- B. Getting a wig or other head cover to avoid heat loss
- C. Avoiding exposure to sunlight or use of a sunscreen and protective clothing if exposure is inevitable
- D. Providing frequent rest periods in a dark room
Correct Answer: C
Rationale: Photosensitivity from antibiotics increases sunburn risk; avoiding sunlight or using protection prevents serious skin reactions.
Data in the electronic health record that the provider reviews prior to a patient encounter varies with the clinic setting. In an urgent care clinic, the provider should review:
- A. The patient's current diagnosis and history
- B. Drugs the patient is currently taking
- C. Any recent previous encounter for the same problem as this visit and what was done
- D. All of the above
Correct Answer: D
Rationale: In urgent care, reviewing diagnosis, medications, and prior encounters ensures comprehensive care.
Which of the following shows high first pass metabolism:
- A. Propranolol
- B. Phenobarbitone
- C. Phenylbutazone
- D. Phenytoin
Correct Answer: A
Rationale: Propranolol undergoes extensive first-pass metabolism in the liver.
Plasma concentration of drug at time 0 is 96(g/ml). If t½ is 2 hours concentration in plasma at 10 hours will be
- A. 48
- B. 24
- C. 12
- D. 3
Correct Answer: D
Rationale: In first-order kinetics, the concentration halves every half-life (t½ = 2 hours). At 10 hours (5 half-lives), 96 → 48 → 24 → 12 → 6 → 3 µg/ml.