Quizlet Genitourinary System Related

Review Quizlet Genitourinary System related questions and content

The main reason for the use of combination therapy in the drug treatment of Tuberculosis is:

  • A. Reduce the incidence of side effects
  • B. Delay or prevent the emergence of resistance
  • C. Synergistically increase antimycobacterial activity
  • D. Provide prophylaxis against other bacterial infections
Correct Answer: B

Rationale: The main reason for using combination therapy in TB treatment is to delay or prevent the emergence of resistance. Step 1: TB is caused by Mycobacterium tuberculosis, which has a high mutation rate leading to drug resistance. Step 2: With combination therapy, multiple drugs target different aspects of the bacteria's lifecycle, making it harder for resistance to develop. Step 3: This approach ensures that if one drug becomes ineffective due to resistance, others can still be effective. Summary: Choice B is correct as it directly addresses the issue of resistance, which is a critical concern in TB treatment. Choices A, C, and D are incorrect because reducing side effects, increasing antimycobacterial activity, and providing prophylaxis against other bacterial infections are not the primary reasons for using combination therapy in TB.